{"id":"W4389553027","doi":"10.26508/lsa.202201751","title":"Human RAD52 stimulates the RAD51-mediated homology search","year":2023,"lang":"en","type":"article","venue":"Life Science Alliance","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research; Fondation Gustave Roussy; Institut Gustave-Roussy; Agence Nationale de la Recherche","keywords":"RAD51; RAD52; Homologous recombination; Cell biology; Biology; DNA repair; Mediator; Homology directed repair; DNA; Genetics; Nucleotide excision repair","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001042093,0.000128232,0.0001099158,0.00005326414,0.0004837596,0.00006368472,0.001089924,0.00008998762,0.00004086892],"category_scores_gemma":[0.0004404469,0.00009618101,0.00005350562,0.0009325078,0.0009406023,0.00001045669,0.0003931119,0.0001336883,0.0004299502],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001550451,"about_ca_system_score_gemma":0.0002497172,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001884308,"about_ca_topic_score_gemma":0.00001223623,"domain_scores_codex":[0.9982472,0.00007008168,0.0001658014,0.0005482067,0.0003742569,0.0005944269],"domain_scores_gemma":[0.9989967,0.00003408113,0.00004912272,0.0006603535,0.0001046358,0.0001551067],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000007233871,0.00001450987,0.001382932,0.000005035121,0.000009267491,0.000007900035,0.0000858471,0.0005678617,0.9939227,0.0007926657,0.002854205,0.0003498062],"study_design_scores_gemma":[0.0007671457,0.0005339992,0.0440804,0.00002228295,0.00001194832,0.00002645816,0.0004679073,0.007779055,0.9145455,0.001373492,0.02987812,0.0005137084],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967596,0.0002177748,0.0001120467,0.001510685,0.0003250108,0.0002159992,0.000008429823,0.00008340277,0.0007670489],"genre_scores_gemma":[0.9954277,0.00009819023,0.0003003401,0.001021885,0.000174873,0.00002791858,0.00002664863,0.00001650359,0.00290598],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07937726,"threshold_uncertainty_score":0.5526283,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02743191292815997,"score_gpt":0.3146898723570165,"score_spread":0.2872579594288565,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}