{"id":"W4389553027","doi":"10.26508/lsa.202201751","title":"Human RAD52 stimulates the RAD51-mediated homology search","year":2023,"lang":"en","type":"article","venue":"Life Science Alliance","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research; Fondation Gustave Roussy; Institut Gustave-Roussy; Agence Nationale de la Recherche","keywords":"RAD51; RAD52; Homologous recombination; Cell biology; Biology; DNA repair; Mediator; Homology directed repair; DNA; Genetics; Nucleotide excision repair","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001080614,0.0002154984,0.00009916558,0.0001055402,0.00007891768,0.0001543765,0.00009099543,0.0001753838,0.004543221],"category_scores_gemma":[0.00009513908,0.00009368763,0.0001446693,0.00005900309,0.00007548718,0.0001050813,0.0001597784,0.000201937,0.001015463],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001427914,"about_ca_system_score_gemma":0.00007568511,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002624142,"about_ca_topic_score_gemma":0.0005384773,"domain_scores_codex":[0.9999075,0.0000198567,0.000004340339,0.00002878248,0.00001764184,0.00002193574],"domain_scores_gemma":[0.9999471,0.00001322068,0.000009272994,0.000009735666,0.000005721928,0.00001499086],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003393107,0.00001015614,0.0001927158,0.00001845344,0.000002623129,0.00002700452,0.000006307304,0.00001289668,0.9987842,0.00006067055,0.00003388971,0.0008171495],"study_design_scores_gemma":[0.00001049527,0.0001482859,0.01204276,0.000006244721,0.000006692921,0.0002446573,0.000014154,0.0004164964,0.9848027,0.00003557597,0.002269552,0.000002480106],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9884167,0.002943988,0.002829026,0.00008886986,0.00003155068,0.00002045272,0.0002261164,0.00009423732,0.005348976],"genre_scores_gemma":[0.994198,0.0004324422,0.0009967405,0.00002860827,0.00000570211,0.000009835258,0.0003085398,0.000009528641,0.004010647],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004543221,"threshold_uncertainty_score":0.01519859,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02743191292815997,"score_gpt":0.3146898723570165,"score_spread":0.2872579594288565,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}