{"id":"W4389555309","doi":"10.1001/jama.2023.24945","title":"Continued Treatment With Tirzepatide for Maintenance of Weight Reduction in Adults With Obesity","year":2023,"lang":"en","type":"article","venue":"JAMA","topic":"Bariatric Surgery and Outcomes","field":"Medicine","cited_by":709,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; York University","funders":"National Center for Advancing Translational Sciences","keywords":"Medicine; Weight loss; Placebo; Randomization; Body mass index; Obesity; Randomized controlled trial; Clinical endpoint; Weight change; Surgery; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00137185,0.0004014776,0.001054011,0.0001785739,0.0002450017,0.0004277964,0.0004336542,0.000768695,0.002454716],"category_scores_gemma":[0.002004685,0.0001875085,0.0008873816,0.0001971984,0.0002839656,0.0004468373,0.000199763,0.001003074,0.0002641489],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002372932,"about_ca_system_score_gemma":0.0005745824,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006166809,"about_ca_topic_score_gemma":0.002215053,"domain_scores_codex":[0.9995348,0.000236733,0.00006665185,0.00004715505,0.00007209904,0.00004255248],"domain_scores_gemma":[0.9990129,0.0003596749,0.0003566106,0.00004383694,0.00007657665,0.0001503237],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.3912422,0.01415498,0.035057,0.006912562,0.003786793,0.0002871632,0.0004110675,0.0006001275,0.025754,0.0001805627,0.003106846,0.5185068],"study_design_scores_gemma":[0.466323,0.3367426,0.1769263,0.001293798,0.003869339,0.0007972904,0.0002952312,0.001542696,0.005070206,0.000267194,0.006823125,0.00004928781],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9760358,0.01983116,0.0005582983,0.0007312731,0.000194138,0.0008540803,0.0003140174,0.00005707332,0.001424104],"genre_scores_gemma":[0.9905671,0.005309453,0.001785595,0.0005562237,0.0002440214,0.0008163749,0.0002091845,0.000006668016,0.0005054303],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002454716,"threshold_uncertainty_score":0.008211911,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01151115149550049,"score_gpt":0.2411257520010505,"score_spread":0.22961460050555,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}