{"id":"W4389564064","doi":"10.3390/cells12242807","title":"The Identification of Nuclear FMRP Isoform Iso6 Partners","year":2023,"lang":"en","type":"article","venue":"Cells","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"PROTEO; Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada; Cancer Research Society; Université Laval","keywords":"Gene isoform; Biology; RNA splicing; RNA-binding protein; Cell biology; Nuclear transport; Alternative splicing; Nuclear export signal; Ribosome biogenesis; Genetics; Cell nucleus; RNA; Cytoplasm; Gene; Ribosome","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001188428,0.00005312594,0.00003963771,0.00001550487,0.00008584635,0.00001448407,0.0001467985,0.000036908,0.000007511379],"category_scores_gemma":[0.00001649436,0.00004256373,0.00003988732,0.00009177002,0.00006008472,8.632082e-7,0.00007188944,0.00002300788,0.0001242034],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002310154,"about_ca_system_score_gemma":0.00001592701,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001852936,"about_ca_topic_score_gemma":0.000004217922,"domain_scores_codex":[0.9995101,0.00001205778,0.0001521665,0.0001273571,0.00007334878,0.0001249559],"domain_scores_gemma":[0.9996939,0.000006466953,0.00005435904,0.0001969355,0.00002512894,0.00002324432],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000078709,0.000008764498,0.00006765607,0.000005818339,0.000009056147,1.86571e-7,0.00004838415,0.0000486853,0.9781004,0.00007638297,0.01971295,0.001913906],"study_design_scores_gemma":[0.0001122632,0.00004391917,0.01430925,0.000001782695,0.00000401611,4.097479e-7,0.0002504497,0.0001283669,0.7575059,0.0001148608,0.2274589,0.00006991806],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973446,0.0001054797,0.00001682124,0.0002100509,0.0002017196,0.00008626632,0.000006207878,0.000009391477,0.002019497],"genre_scores_gemma":[0.9958163,0.001147354,0.00002181221,0.0000899887,0.000009846694,0.000005241042,0.00003114691,0.00001234977,0.002865952],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2205945,"threshold_uncertainty_score":0.1735699,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009947358769292805,"score_gpt":0.2472102288541811,"score_spread":0.2372628700848882,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}