{"id":"W4389571392","doi":"10.1080/14786419.2023.2290688","title":"Tetrahydroquinoline-containing natural products discovered within the last decade: occurrence and bioactivity","year":2023,"lang":"en","type":"review","venue":"Natural Product Research","topic":"Chemical synthesis and alkaloids","field":"Chemistry","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Canada","funders":"","keywords":"Drug discovery; Natural (archaeology); Natural product; Biology; Computational biology; Bioinformatics; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001966017,0.0004206041,0.0005168235,0.001579153,0.0002403526,0.0006482243,0.0003817167,0.0004531991,0.002867572],"category_scores_gemma":[0.0002475839,0.0001847971,0.0002638748,0.001424239,0.0002964061,0.0008376318,0.0003770058,0.0007904496,0.001358342],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003707678,"about_ca_system_score_gemma":0.0005534258,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006138538,"about_ca_topic_score_gemma":0.00150488,"domain_scores_codex":[0.999898,0.000008709067,0.00001102184,0.0000272638,0.00004352137,0.00001160848],"domain_scores_gemma":[0.9998951,0.00003791989,0.00002273754,0.000004487047,0.00003078629,0.000008974868],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007931882,0.00009764023,0.0003743978,0.02407002,0.00005559215,0.0004300511,0.000151913,0.0005762115,0.02974234,0.007212665,0.008080873,0.929129],"study_design_scores_gemma":[0.000008884146,0.0001775589,0.001194658,0.001697589,0.000075127,0.002414992,0.00008989192,0.0001562911,0.007889672,0.001853521,0.9844192,0.00002256023],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001003695,0.9955717,0.0003050056,0.0001080652,0.00009208673,0.000007042186,0.00003898867,0.00001291034,0.002860493],"genre_scores_gemma":[0.006960249,0.9903734,0.0005185546,0.0001318698,0.00009692282,0.000008428366,0.00006495843,0.000003202768,0.001842459],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002867572,"threshold_uncertainty_score":0.00959301,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1414541759154802,"score_gpt":0.4134813397127596,"score_spread":0.2720271637972794,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}