{"id":"W4389573987","doi":"10.3390/diagnostics13243639","title":"Evaluation of a Point-of-Need Molecular Diagnostic Tool Coupled with Rapid DNA Extraction Methods for Visceral Leishmaniasis","year":2023,"lang":"en","type":"article","venue":"Diagnostics","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Global Affairs Canada; Department for International Development; International Centre for Diarrhoeal Disease Research, Bangladesh; Styrelsen för Internationellt Utvecklingssamarbete","keywords":"Recombinase Polymerase Amplification; DNA extraction; Visceral leishmaniasis; Molecular biology; Polymerase chain reaction; DNA; Real-time polymerase chain reaction; Nucleic acid; Biology; Assay sensitivity; Leishmania donovani; Loop-mediated isothermal amplification; Leishmaniasis; Medicine; Immunology; Pathology; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.004357794,0.0002383256,0.0006629441,0.0004077288,0.00008561324,0.00001937324,0.0001322888,0.0001195162,0.00009485619],"category_scores_gemma":[0.06267425,0.000203529,0.0001874737,0.0008552147,0.000184868,0.0001258657,0.00007351986,0.0001788728,0.00001210669],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001695158,"about_ca_system_score_gemma":0.0003905859,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005826591,"about_ca_topic_score_gemma":0.00001767981,"domain_scores_codex":[0.9968735,0.0003963112,0.000596141,0.0003724743,0.001337095,0.0004244863],"domain_scores_gemma":[0.9860597,0.01033244,0.0002994247,0.000490822,0.002704052,0.0001135163],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.003310839,0.003483693,0.07342881,0.004336361,0.00619165,0.0003203892,0.003817474,0.007059077,0.2622445,0.003369756,0.0227941,0.6096433],"study_design_scores_gemma":[0.01630297,0.006460362,0.4401094,0.001525982,0.007303244,0.0000659037,0.002223381,0.1910647,0.3290806,0.003460037,0.001620898,0.0007823933],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9478139,0.001317244,0.04486216,0.00135348,0.0002349128,0.003802649,0.00007078935,0.0001172458,0.0004275698],"genre_scores_gemma":[0.9677456,0.001840819,0.02881119,0.00008884501,0.0001138281,0.00109869,0.0001723804,0.00007871273,0.00004995327],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.608861,"threshold_uncertainty_score":0.9452212,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06521668608357638,"score_gpt":0.4200739074333165,"score_spread":0.3548572213497401,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}