{"id":"W4389578921","doi":"10.1136/bmjophth-2023-001346","title":"Evaluating the long-term biological stability of cytokine biomarkers in ocular fluid samples","year":2023,"lang":"en","type":"article","venue":"BMJ Open Ophthalmology","topic":"Retinal and Macular Surgery","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Western Hospital; University Health Network; Kensington Health; St. Michael's Hospital; University of Toronto","funders":"","keywords":"Biomarker; Cytokine; Medicine; Aqueous humor; Multiplex; Aqueous humour; Ophthalmology; Immunology; Chemistry; Biology; Bioinformatics; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003139494,0.0006382789,0.0005151451,0.0007534199,0.0005126301,0.001127157,0.0003176856,0.000594385,0.001025662],"category_scores_gemma":[0.00398441,0.0001971619,0.000429797,0.0006860887,0.0006507542,0.0008087881,0.0003982896,0.0005080579,0.0003736114],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004741236,"about_ca_system_score_gemma":0.0005832379,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001065323,"about_ca_topic_score_gemma":0.001003726,"domain_scores_codex":[0.998592,0.0003285232,0.0002289148,0.0002639546,0.0004864444,0.0001001724],"domain_scores_gemma":[0.9975304,0.0006207883,0.0008444089,0.0002281963,0.0006972735,0.00007893913],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002174178,0.0001905737,0.08005042,0.0004538454,0.0001876531,0.0002926708,0.0003909458,0.0004958159,0.8838319,0.0001006635,0.0001838541,0.03164741],"study_design_scores_gemma":[0.00004078714,0.003368847,0.2186117,0.0001647777,0.0003129623,0.001321617,0.0006146731,0.00190169,0.7699078,0.0001621841,0.003532542,0.00006043968],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.977334,0.01381738,0.007105083,0.0001673028,0.00009251692,0.0001396616,0.0006510779,0.00005698933,0.0006360594],"genre_scores_gemma":[0.9869148,0.002893724,0.008088652,0.0001682246,0.00007642514,0.0001725315,0.0009682368,0.00002393478,0.0006934206],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003139494,"threshold_uncertainty_score":0.01660341,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3481392567767392,"score_gpt":0.4876070689354814,"score_spread":0.1394678121587422,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}