{"id":"W4389606303","doi":"10.1016/j.celrep.2023.113565","title":"Ratcheted transport and sequential assembly of the yeast telomerase RNP","year":2023,"lang":"en","type":"article","venue":"Cell Reports","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Ribonucleoprotein; Telomerase; Telomere; Cell biology; Protein subunit; RNA; Biology; Nuclear export signal; Cytoplasm; Ribonucleoprotein particle; Telomerase RNA component; DNA; Genetics; Telomerase reverse transcriptase; Cell nucleus; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001567955,0.0002688735,0.0001355182,0.0001252834,0.0001445296,0.0003676432,0.0001677981,0.0001918031,0.0005092611],"category_scores_gemma":[0.000194888,0.000159117,0.0002166296,0.00009398587,0.0002074977,0.0003266867,0.0003229567,0.0003855434,0.0003480819],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002125665,"about_ca_system_score_gemma":0.00019702,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007492179,"about_ca_topic_score_gemma":0.00107441,"domain_scores_codex":[0.9999155,0.00001033669,0.000005239776,0.00002908069,0.00002314655,0.00001675456],"domain_scores_gemma":[0.9999038,0.00001249153,0.00002425316,0.00002358633,0.00001833178,0.00001753523],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001420266,0.00001880828,0.0005761288,0.00005395938,0.00000715496,0.0003217077,0.00005748977,0.0003990604,0.9881058,0.001536908,0.0001244231,0.008656583],"study_design_scores_gemma":[0.00002185529,0.0002597506,0.003807307,0.000006634438,0.00001216851,0.0005216899,0.00005161136,0.003321939,0.9863387,0.0003146743,0.005332334,0.00001138914],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.974812,0.002565397,0.0200637,0.00009241636,0.00008796081,0.00003177234,0.00009261532,0.0003005537,0.001953724],"genre_scores_gemma":[0.9902481,0.0005656839,0.005117955,0.00003222738,0.00001589083,0.00001509836,0.0001818689,0.00003284549,0.00379019],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007492179,"threshold_uncertainty_score":0.00170368,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01849231351475185,"score_gpt":0.2535443690745933,"score_spread":0.2350520555598415,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}