{"id":"W4389615885","doi":"10.34133/research.0295","title":"Activable Photodynamic DNA Probe with an “AND” Logic Gate for Precision Skin Cancer Therapy","year":2023,"lang":"en","type":"article","venue":"Research","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"SKiN Health","funders":"Natural Science Foundation of Hainan Province","keywords":"Photodynamic therapy; Skin cancer; Cancer; Cancer therapy; Medicine; Nanotechnology; Cancer research; Computer science; Materials science; Chemistry; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001292278,0.0003140515,0.0001818365,0.0001306191,0.0001111841,0.0003239719,0.0002808266,0.0004526326,0.001052059],"category_scores_gemma":[0.0001388016,0.000158002,0.0001110258,0.0001299281,0.000289079,0.0004337042,0.0002389892,0.0003598845,0.0003280056],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004022131,"about_ca_system_score_gemma":0.0002015811,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000202115,"about_ca_topic_score_gemma":0.0002460446,"domain_scores_codex":[0.9998959,0.00001577789,0.000007549822,0.00003055582,0.00003260875,0.00001756998],"domain_scores_gemma":[0.9999459,0.00001182986,0.00002130116,0.000004030807,0.000007269284,0.000009664203],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004316173,0.00002088821,0.00004049819,0.00006832268,0.000002923962,0.00006489064,0.00001841994,0.0005237887,0.9913836,0.001428313,0.0001815207,0.006223782],"study_design_scores_gemma":[0.00002058386,0.0001146547,0.00013092,0.000003401409,0.000006528118,0.0001142645,0.000005340395,0.004987889,0.9888335,0.0002324436,0.005540413,0.00001007312],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8249623,0.007250278,0.1484591,0.001160197,0.0003938736,0.0002232761,0.0003338935,0.0009705974,0.01624646],"genre_scores_gemma":[0.9471633,0.001878035,0.04470185,0.0003670127,0.00004103085,0.00007198192,0.00008971684,0.00003626354,0.005650891],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001052059,"threshold_uncertainty_score":0.003519475,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06480247585289668,"score_gpt":0.4302646365439388,"score_spread":0.3654621606910421,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}