{"id":"W4389616832","doi":"10.5530/ptb.2023.9.12","title":"Drug Review: Vonoprazan","year":2023,"lang":"en","type":"article","venue":"Pharmacology Toxicology and Biomedical Reports","topic":"Chemical Reactions and Isotopes","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Chemistry; Pharmacology; Medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.002276062,0.0003581578,0.0006421881,0.0002985336,0.0004530008,0.00001270835,0.0002398252,0.0006594457,0.009525134],"category_scores_gemma":[0.0007287676,0.0003070275,0.0001639902,0.0008925067,0.001342292,0.0001332437,0.0003560392,0.001408831,0.0007672222],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000697422,"about_ca_system_score_gemma":0.0002210652,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001810906,"about_ca_topic_score_gemma":0.000006071829,"domain_scores_codex":[0.9965962,0.000461893,0.0008916397,0.0008116913,0.0002650014,0.0009736209],"domain_scores_gemma":[0.9973463,0.00111637,0.000294558,0.0002517162,0.0001231738,0.0008678436],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001013865,0.0004484697,0.003016583,0.000270387,0.0002541774,0.00268029,0.00008245192,0.000001747818,0.2084341,0.0002923059,0.751357,0.03306107],"study_design_scores_gemma":[0.0008587542,0.0001461878,0.00284521,0.00005763054,0.0003625806,0.001315303,0.00003957726,0.0002254063,0.02382968,0.001641073,0.9683321,0.000346539],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8997797,0.01293902,0.00003545185,0.06407741,0.008598122,0.001201514,0.00005622042,0.001000626,0.01231193],"genre_scores_gemma":[0.8969877,0.05340983,0.0001071489,0.03917792,0.00103622,0.000459404,0.0002321543,0.00004828025,0.008541328],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.216975,"threshold_uncertainty_score":0.9999382,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07103722422864682,"score_gpt":0.4484259053454758,"score_spread":0.3773886811168289,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}