{"id":"W4389621524","doi":"10.1681/asn.0000000000000271","title":"Effects of Empagliflozin on Fluid Overload, Weight, and Blood Pressure in CKD","year":2023,"lang":"en","type":"article","venue":"Journal of the American Society of Nephrology","topic":"Body Composition Measurement Techniques","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Health Data Research UK; National Heart, Lung, and Blood Institute; National Center for Advancing Translational Sciences; Medical Research Council; Centers for Disease Control and Prevention; Fresenius Medical Care North America; Astellas Pharma; National Institute on Minority Health and Health Disparities; Deutsche Forschungsgemeinschaft; Amicus Therapeutics; University of Oxford; Regeneron Pharmaceuticals; National Institutes of Health; Biomedical Research Council; Kidney Research UK; Novo Nordisk; National Institute for Health and Care Research; Pfizer; Moderna; British Heart Foundation; Alnylam Pharmaceuticals; Amgen; European Society of Cardiology; Science Foundation Ireland; Eli Lilly and Company; AstraZeneca; American Heart Association; American Society of Nephrology; National Institute of Diabetes and Digestive and Kidney Diseases; Sanofi","keywords":"Empagliflozin; Medicine; Internal medicine; Copeptin; Population; Placebo; Cardiology; Diabetes mellitus; Kidney disease; Type 2 diabetes; Urology; Endocrinology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001802218,0.0004587306,0.001706633,0.0002999896,0.000227758,0.0004499168,0.0003645868,0.0007732965,0.001775293],"category_scores_gemma":[0.002192475,0.0002455719,0.001213784,0.0002571327,0.0003106146,0.0004385514,0.0003712702,0.001251429,0.0001438769],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003440282,"about_ca_system_score_gemma":0.0005489099,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008093282,"about_ca_topic_score_gemma":0.001734812,"domain_scores_codex":[0.9995428,0.0002139485,0.00005478317,0.00004839616,0.00007646975,0.00006349028],"domain_scores_gemma":[0.9990422,0.0003585418,0.0002245051,0.00006700602,0.00008744426,0.000220247],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8252707,0.01016572,0.01800536,0.002117012,0.003322537,0.00009326905,0.0001039484,0.0008233528,0.01030225,0.0001174883,0.00218639,0.1274919],"study_design_scores_gemma":[0.3144361,0.2550274,0.4009086,0.0003912398,0.00908124,0.0002529479,0.0001060832,0.003947763,0.01035235,0.0003747276,0.005029849,0.00009159838],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9851164,0.01190534,0.0002485464,0.0005159588,0.0001751847,0.000310086,0.0005511641,0.00004880084,0.001128473],"genre_scores_gemma":[0.9948956,0.002451511,0.0007249883,0.0004378352,0.000190315,0.0003650031,0.0003617474,0.000005303369,0.000567589],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001802218,"threshold_uncertainty_score":0.00953114,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01100247572209583,"score_gpt":0.2692438074211832,"score_spread":0.2582413316990874,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}