{"id":"W4389669794","doi":"10.1038/s41435-023-00240-9","title":"An adjunct microbiome therapy to enhance immunotherapy efficacy in melanoma patients","year":2023,"lang":"en","type":"article","venue":"Genes and Immunity","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ontario Institute for Cancer Research; Lawson Health Research Institute; Western University","funders":"","keywords":"Adjunct; Biology; Microbiome; Immunotherapy; Melanoma; Immunology; Bioinformatics; Immune system; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001426556,0.0001060614,0.0004158062,0.0001402246,0.0002583133,0.0002507903,0.00009352928,0.000218063,0.002617807],"category_scores_gemma":[0.0002696557,0.00005638856,0.0002274949,0.0001133896,0.00008039806,0.000171141,0.0001849564,0.000534244,0.000278993],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001477863,"about_ca_system_score_gemma":0.0002400155,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000213153,"about_ca_topic_score_gemma":0.0007251136,"domain_scores_codex":[0.9999481,0.00001600234,0.000003309672,0.000008278328,0.000008856695,0.00001540861],"domain_scores_gemma":[0.9999318,0.00001161277,0.00001169233,0.000004236608,0.000006400431,0.00003417835],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.03622112,0.01206757,0.02318675,0.001075655,0.0004374736,0.0007995518,0.0002688491,0.0009964438,0.127393,0.0008099475,0.005700964,0.7910426],"study_design_scores_gemma":[0.02429117,0.3173913,0.4381815,0.001681201,0.003140028,0.006583405,0.00118739,0.0106096,0.09141238,0.003761941,0.1016353,0.0001248288],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.989019,0.00651626,0.0003678816,0.0007689242,0.0002158819,0.0001100736,0.00007650041,0.00004646414,0.002879024],"genre_scores_gemma":[0.9956859,0.001553263,0.0009083602,0.0003919486,0.00008719414,0.00009040335,0.00007470339,0.000004506226,0.001203712],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002617807,"threshold_uncertainty_score":0.008757412,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01092791351382254,"score_gpt":0.2973336874970028,"score_spread":0.2864057739831803,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}