{"id":"W4389683409","doi":"10.1186/s13195-023-01356-w","title":"NeuroEPO plus (NeuralCIM®) in mild-to-moderate Alzheimer’s clinical syndrome: the ATHENEA randomized clinical trial","year":2023,"lang":"en","type":"article","venue":"Alzheimer s Research & Therapy","topic":"Erythropoietin and Anemia Treatment","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Placebo; Internal medicine; Randomized controlled trial; Montreal Cognitive Assessment; Gastroenterology; Cognitive impairment; Disease; Pathology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008774833,0.0007527318,0.001458944,0.0002735998,0.0002335681,0.0006822557,0.000593121,0.0009702496,0.00467202],"category_scores_gemma":[0.0008546814,0.0002574516,0.0008626418,0.000207076,0.0004176861,0.0004694524,0.0002553953,0.001103864,0.0004509249],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003821551,"about_ca_system_score_gemma":0.0006560761,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006873144,"about_ca_topic_score_gemma":0.002317657,"domain_scores_codex":[0.9997261,0.000163215,0.00001902095,0.00003466922,0.00002847339,0.00002839586],"domain_scores_gemma":[0.9997475,0.00006600853,0.00007171118,0.00001656549,0.00002419924,0.00007407248],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9623657,0.003586805,0.001529317,0.001524378,0.001379787,0.00008406735,0.0000412102,0.0002107531,0.00171322,0.0002742324,0.001575385,0.02571508],"study_design_scores_gemma":[0.9674841,0.0245054,0.004947014,0.0001216263,0.0006701855,0.0000624452,0.00002311259,0.0003756596,0.0001970071,0.0002515572,0.001349478,0.0000125141],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9738236,0.0150288,0.0004697306,0.0008311057,0.00056044,0.002733992,0.001054724,0.00006813759,0.005429407],"genre_scores_gemma":[0.9776565,0.00642146,0.001419409,0.001456325,0.0005579682,0.005609937,0.001267347,0.00001093717,0.005599997],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00467202,"threshold_uncertainty_score":0.01562947,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.4803052494384483,"score_gpt":0.544363344482378,"score_spread":0.06405809504392973,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}