{"id":"W4389702450","doi":"10.1101/2023.12.11.23299838","title":"Regional changes in cellular and molecular pathology in children with end-stage dilated cardiomyopathy: Correlation with regional and global cardiac performance","year":2023,"lang":"en","type":"preprint","venue":"medRxiv","topic":"Cardiovascular Function and Risk Factors","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Ejection fraction; Dilated cardiomyopathy; Cardiology; Internal medicine; Medicine; Fibrosis; Myocardial fibrosis; Cardiac myocyte; Cardiomyopathy; Myocyte; Phospholamban; Cardiac fibrosis; Cardiac function curve; Heart failure","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004186831,0.0003421934,0.0002813181,0.0005476173,0.0002120776,0.0004274943,0.000228523,0.0003569593,0.002056158],"category_scores_gemma":[0.001256594,0.0001675125,0.0002296059,0.0004289011,0.0003270516,0.0003614974,0.0004472536,0.0004227576,0.0002831495],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002081834,"about_ca_system_score_gemma":0.0001873494,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001073832,"about_ca_topic_score_gemma":0.001200454,"domain_scores_codex":[0.9996942,0.000059666,0.00003192259,0.00008901474,0.00005167864,0.00007345458],"domain_scores_gemma":[0.9989341,0.0001853167,0.000493042,0.0000483333,0.0001082977,0.0002310191],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00006138837,0.00001047048,0.9985254,0.000007391075,0.00001207821,0.0001274819,0.0000324178,0.00003651699,0.0003509334,0.000009259828,0.00002918227,0.0007975174],"study_design_scores_gemma":[0.000001840006,0.00009310904,0.9988954,0.000004127186,0.000009938073,0.0006439943,0.00009347248,0.00005351894,0.000126296,0.00001118512,0.00006538058,0.000001664593],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992741,0.0002595679,0.00008757706,0.00001700966,0.000002008088,0.000002938584,0.0001584715,0.000003203842,0.0001951344],"genre_scores_gemma":[0.9995168,0.00008461037,0.00009070921,0.000005979869,0.000004196475,0.000005204158,0.000193572,0.000001557369,0.00009736477],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002056158,"threshold_uncertainty_score":0.006878495,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01446787664135579,"score_gpt":0.2244148967498782,"score_spread":0.2099470201085225,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}