{"id":"W4389740289","doi":"10.14309/01.ajg.0000995740.88073.c5","title":"S1 Risankizumab Versus Ustekinumab in Patients With Moderate to Severe Crohn’s Disease: Results From the Phase 3B SEQUENCE Trial","year":2023,"lang":"en","type":"article","venue":"The American Journal of Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Medicine; Ustekinumab; Crohn disease; Crohn's disease; Sequence (biology); Dermatology; Disease; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002847896,0.0009415864,0.00226061,0.0002692737,0.0003101232,0.0009360893,0.0005066519,0.001211302,0.005019673],"category_scores_gemma":[0.002302219,0.0003427958,0.002680796,0.0002762904,0.0007226914,0.0007449538,0.0003728902,0.002328079,0.000946704],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005641744,"about_ca_system_score_gemma":0.001170973,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004655305,"about_ca_topic_score_gemma":0.001246227,"domain_scores_codex":[0.999126,0.0005766182,0.00006405086,0.00008410666,0.00006345697,0.00008565118],"domain_scores_gemma":[0.998687,0.0003926793,0.0003485616,0.0001016595,0.0001030845,0.0003670638],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9683598,0.002659449,0.0009230116,0.0007681992,0.001094827,0.00003614708,0.00005120685,0.0003968593,0.002203287,0.0001250332,0.001528931,0.02185326],"study_design_scores_gemma":[0.9073103,0.08445382,0.004352438,0.0001280595,0.0009302198,0.0000961355,0.00002593586,0.0005246295,0.0003592248,0.0003463264,0.001455121,0.00001789358],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9768511,0.01377249,0.0005687381,0.001869908,0.0005970131,0.001396305,0.001465608,0.0001121014,0.003366633],"genre_scores_gemma":[0.986048,0.004459608,0.001450108,0.00202934,0.0005589821,0.001675318,0.001961565,0.00002989111,0.001787237],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005019673,"threshold_uncertainty_score":0.01679248,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0147505105914606,"score_gpt":0.2704752404634666,"score_spread":0.255724729872006,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}