{"id":"W4389740384","doi":"10.14309/01.ajg.0000995752.19097.c8","title":"S4 Risankizumab Induction Therapy in Patients With Moderately to Severely Active Ulcerative Colitis: Efficacy and Safety in the Randomized Phase 3 INSPIRE Study","year":2023,"lang":"en","type":"article","venue":"The American Journal of Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Medicine; Ulcerative colitis; Internal medicine; Randomized controlled trial; Gastroenterology; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004222855,0.0008158121,0.002106896,0.0002275566,0.000341262,0.0007947944,0.0007837143,0.001114748,0.005228725],"category_scores_gemma":[0.002272398,0.0003843446,0.002782828,0.0002846509,0.0005335677,0.0005278119,0.0004195739,0.00218959,0.00071286],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006356088,"about_ca_system_score_gemma":0.001390906,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006940194,"about_ca_topic_score_gemma":0.002907325,"domain_scores_codex":[0.9987913,0.0008208509,0.00007697463,0.00009795643,0.0001163339,0.00009669054],"domain_scores_gemma":[0.9987295,0.0003108757,0.0003896024,0.0001340322,0.0001444668,0.0002916101],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.948507,0.004165733,0.003757986,0.001010513,0.002231278,0.00007636905,0.00007204595,0.0004670166,0.004623365,0.0001539966,0.003434763,0.0315],"study_design_scores_gemma":[0.891803,0.0879242,0.01375171,0.0001166211,0.001781743,0.0001464068,0.00002254674,0.0006175268,0.0007999847,0.0001853533,0.002827257,0.00002356094],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.972353,0.01014131,0.0010612,0.001437512,0.000290755,0.005782687,0.003638736,0.0002039077,0.005090957],"genre_scores_gemma":[0.9781643,0.003453726,0.003061183,0.00234088,0.000361574,0.004994594,0.004948585,0.00003740541,0.002637587],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005228725,"threshold_uncertainty_score":0.02233285,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008223645705691568,"score_gpt":0.2652600689223643,"score_spread":0.2570364232166727,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}