{"id":"W4389743695","doi":"10.1016/j.celrep.2023.113574","title":"Microglia promote remyelination independent of their role in clearing myelin debris","year":2023,"lang":"en","type":"article","venue":"Cell Reports","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; Women and Children’s Health Research Institute; University of Alberta","funders":"","keywords":"Remyelination; Microglia; Myelin; Multiple sclerosis; Neuroscience; Biology; Progenitor cell; Oligodendrocyte; Cell biology; Immunology; Stem cell; Central nervous system; Inflammation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003194941,0.0004563418,0.0003066837,0.0004633871,0.0003556065,0.0005393562,0.0001691523,0.0004478374,0.00133018],"category_scores_gemma":[0.0002391703,0.0001714997,0.0002717618,0.0001824943,0.0003022855,0.000407908,0.0004236682,0.0005339142,0.0009142421],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002115204,"about_ca_system_score_gemma":0.0003999637,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006058355,"about_ca_topic_score_gemma":0.001246906,"domain_scores_codex":[0.9997221,0.00006274287,0.00001751895,0.00003313647,0.00007943061,0.00008519638],"domain_scores_gemma":[0.9997892,0.00003077196,0.00006802271,0.00002444107,0.00004881922,0.00003865485],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002158792,0.00003395232,0.0006767267,0.0001615301,0.00001009339,0.0002414262,0.0001226457,0.00006594777,0.9891933,0.0008184717,0.0001610268,0.008298965],"study_design_scores_gemma":[0.00005033635,0.0005497764,0.0163982,0.000176179,0.0000659839,0.001329408,0.0003647247,0.000735492,0.9531615,0.001294637,0.02586035,0.00001331504],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9436507,0.02919472,0.01114893,0.0008527652,0.0001364113,0.00008098348,0.0003677148,0.0002872908,0.01428039],"genre_scores_gemma":[0.972504,0.01299307,0.006734462,0.0001985918,0.00008155913,0.00008906562,0.0001694798,0.00004379849,0.00718607],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00133018,"threshold_uncertainty_score":0.004449844,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02446550641284125,"score_gpt":0.244810011631795,"score_spread":0.2203445052189537,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}