{"id":"W4389752877","doi":"10.1016/s0140-6736(23)01857-3","title":"Standard-of-care systemic therapy with or without stereotactic body radiotherapy in patients with oligoprogressive breast cancer or non-small-cell lung cancer (Consolidative Use of Radiotherapy to Block [CURB] oligoprogression): an open-label, randomised, controlled, phase 2 study","year":2023,"lang":"en","type":"article","venue":"The Lancet","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":255,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"National Cancer Institute; National Institutes of Health; Invitae; Susan G. Komen; Breast Cancer Research Foundation","keywords":"Radiation therapy; Medicine; Cancer; Breast cancer; Lung cancer; Standard of care; Stereotactic radiotherapy; Systemic therapy; Oncology; Radiology; Internal medicine; Radiosurgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001261492,0.001198903,0.002720058,0.0004169861,0.0002994025,0.0007066345,0.0007747414,0.001454793,0.005382257],"category_scores_gemma":[0.001057798,0.0005377738,0.001894197,0.0006461944,0.001113966,0.0008529859,0.0003310987,0.002297472,0.0006021673],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009125789,"about_ca_system_score_gemma":0.001138508,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002598824,"about_ca_topic_score_gemma":0.006778446,"domain_scores_codex":[0.9993904,0.0003311434,0.00003201059,0.0001072938,0.00004278301,0.00009634332],"domain_scores_gemma":[0.999328,0.0002170347,0.0001492207,0.00005864523,0.00003734116,0.0002098015],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9709246,0.005670886,0.0008032269,0.0005880671,0.0009544593,0.00002314591,0.00005255036,0.0003011203,0.001913203,0.00005704587,0.0004586412,0.01825307],"study_design_scores_gemma":[0.8821179,0.1119867,0.004080083,0.00003668279,0.0006938539,0.00002477591,0.00003320787,0.0001948514,0.0002836109,0.0000790319,0.0004568252,0.00001251817],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914606,0.004715227,0.0003041041,0.0003174628,0.0002266227,0.0009740677,0.0006064991,0.00004701846,0.001348505],"genre_scores_gemma":[0.9904166,0.0036094,0.0008961463,0.0007096223,0.0002779814,0.001414291,0.000787697,0.00001716152,0.001871077],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005382257,"threshold_uncertainty_score":0.01800549,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02831244113882767,"score_gpt":0.3527839359596867,"score_spread":0.324471494820859,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}