{"id":"W4389789037","doi":"10.1101/2023.12.13.23298992","title":"A multiplex qRT-PCR assay for detection of Influenza A and H5 subtype targeting new SNPs present in high pathogenicity avian influenza Canadian 2022 outbreak strains","year":2023,"lang":"en","type":"preprint","venue":"medRxiv","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Centre for Disease Control","funders":"British Columbia Centre for Disease Control; Canadian Food Inspection Agency","keywords":"Influenza A virus subtype H5N1; Multiplex; Subtyping; Outbreak; Virology; Multiplex polymerase chain reaction; Biology; Pathogenicity; Highly pathogenic; Seasonal influenza; Influenza A virus; Computational biology; Gene; Polymerase chain reaction; Genetics; Virus; Microbiology; Medicine; Coronavirus disease 2019 (COVID-19); Disease; Infectious disease (medical specialty); Computer science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001579486,0.001142852,0.0006468179,0.0008249329,0.0006661656,0.0008722234,0.0006462018,0.000832047,0.00271889],"category_scores_gemma":[0.001195245,0.0005723059,0.0004639337,0.0006737833,0.0009238427,0.0002324123,0.0004302223,0.001026001,0.001534572],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002140776,"about_ca_system_score_gemma":0.002410472,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0211156,"about_ca_topic_score_gemma":0.0474627,"domain_scores_codex":[0.9980609,0.0001580431,0.0000860776,0.0005850894,0.0008683761,0.0002415271],"domain_scores_gemma":[0.9991904,0.0002364155,0.0001013308,0.00008479564,0.0003282545,0.00005869938],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007739886,0.00003314938,0.001115837,0.00006161779,0.000009046104,0.00002225716,0.00009339015,0.0002350192,0.9949754,0.0001709478,0.00061004,0.002595915],"study_design_scores_gemma":[0.00002646587,0.0002316029,0.01037993,0.00002505729,0.00003982345,0.00014704,0.000109886,0.004240753,0.968401,0.0001280732,0.01623521,0.00003522769],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5239368,0.003942045,0.404011,0.001312103,0.001113575,0.00254461,0.0400378,0.005812028,0.01728998],"genre_scores_gemma":[0.3904302,0.002053022,0.5467547,0.001114155,0.0001556989,0.003521193,0.02261562,0.0006118279,0.03274361],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9788844,"threshold_uncertainty_score":0.04198539,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1193841366941653,"score_gpt":0.3669498442467683,"score_spread":0.247565707552603,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}