{"id":"W4389815220","doi":"10.1021/jacs.3c11126","title":"Widespread Family of NAD<sup>+</sup>-Dependent Sulfoquinovosidases at the Gateway to Sulfoquinovose Catabolism","year":2023,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Water Treatment and Disinfection","field":"Environmental Science","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Infection and Immunity; National Health and Medical Research Council; Australian Research Council; European Research Council; Biotechnology and Biological Sciences Research Council; Department of Chemistry, University of York; State Government of Victoria; Walter and Eliza Hall Institute of Medical Research; University of Melbourne; Medical Research Council; Directorate for Biological Sciences; Royal Society; Diamond Light Source","keywords":"NAD+ kinase; Chemistry; Catabolism; Cofactor; Roseobacter; Biochemistry; Sulfur; Gene; Bacteria; Enzyme; Genetics; Biology; Phylogenetics; Clade; Organic chemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001214208,0.0003760226,0.0002034716,0.0004017689,0.0002626742,0.0004857812,0.0002709425,0.0003078358,0.002419508],"category_scores_gemma":[0.0001373749,0.0002202568,0.0002220077,0.0004245247,0.0002484359,0.0004238553,0.0003000489,0.0004742777,0.00120907],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002456892,"about_ca_system_score_gemma":0.0002138237,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005259893,"about_ca_topic_score_gemma":0.00067904,"domain_scores_codex":[0.9998919,0.000006678317,0.00000614302,0.00004926286,0.00003130695,0.00001460967],"domain_scores_gemma":[0.9998827,0.00001240986,0.00002978135,0.00001511674,0.00002322331,0.0000367724],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001408171,0.000009388681,0.003140748,0.00006106364,0.000008329842,0.0001956966,0.0000567816,0.00005214768,0.9830942,0.0004153046,0.0004316152,0.01239388],"study_design_scores_gemma":[0.00003536766,0.0001963346,0.1017729,0.00003693295,0.00003769494,0.002758455,0.0002334256,0.003156252,0.8474484,0.001213686,0.04308105,0.00002948589],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.936922,0.003870487,0.04180193,0.00055047,0.00006328512,0.00007097459,0.004597527,0.002532543,0.009590776],"genre_scores_gemma":[0.936865,0.002232178,0.03761004,0.00016615,0.00003536458,0.00005850184,0.0113108,0.0001584158,0.01156349],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002419508,"threshold_uncertainty_score":0.008094013,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01096881038542118,"score_gpt":0.2379697179928002,"score_spread":0.227000907607379,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}