{"id":"W4389828549","doi":"10.1096/fj.202301936rr","title":"From biosynthesis and beyond—Loss or overexpression of the cytokinin synthesis gene, <i>iptA</i> , alters cytokinesis and mitochondrial and amino acid metabolism in <i>Dictyostelium discoideum</i>","year":2023,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Protist diversity and phylogeny","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University; Trent University","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Dictyostelium discoideum; Multicellular organism; Biology; Cytokinesis; Dictyostelium; Adenylate kinase; Citric acid cycle; Cell biology; Gene; Cytokinin; Transfer RNA; Cell cycle; Biochemistry; Metabolism; Cell division; Cell; RNA; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004272526,0.0002937134,0.0001603774,0.0001222672,0.0001791752,0.0003539319,0.0002077704,0.0002384435,0.0008926908],"category_scores_gemma":[0.00006062272,0.0001346421,0.0003150288,0.0001186417,0.0002435278,0.0003080921,0.0002494719,0.0005708533,0.0003564593],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004426339,"about_ca_system_score_gemma":0.0002523188,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001275956,"about_ca_topic_score_gemma":0.001458625,"domain_scores_codex":[0.9999233,0.0000045427,0.000008236756,0.00002378943,0.00001940441,0.00002070227],"domain_scores_gemma":[0.9999365,0.000007780158,0.00002295565,0.000008001386,0.000006584636,0.00001823852],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002661153,0.000003473724,0.0001644924,0.00002517468,9.613901e-7,0.00002727674,0.000008022017,0.00001704948,0.9991484,0.00006754304,0.00001984592,0.0004911929],"study_design_scores_gemma":[0.000005835153,0.00007725152,0.009043082,0.000008305646,0.000009689784,0.0001754591,0.00003224852,0.0003108016,0.9844242,0.00007645805,0.005832478,0.000004210465],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.98544,0.004933335,0.003090768,0.0002908281,0.00007529043,0.00002458783,0.001348539,0.0001765163,0.004620062],"genre_scores_gemma":[0.9906944,0.001715431,0.001879675,0.0001410856,0.000009312717,0.000025659,0.001317155,0.00003475754,0.00418246],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001275956,"threshold_uncertainty_score":0.003211558,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00998970074690164,"score_gpt":0.2154496780062157,"score_spread":0.205459977259314,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}