{"id":"W4389903484","doi":"10.1016/j.mtbio.2023.100917","title":"Itaconate and citrate releasing polymer attenuates foreign body response in biofabricated cardiac patches","year":2023,"lang":"en","type":"article","venue":"Materials Today Bio","topic":"Tissue Engineering and Regenerative Medicine","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Nova Scotia Health Authority; Dalhousie University; Stem Cell Network; University of Toronto; University Health Network","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Institutes of Health; Canada Foundation for Innovation; Ontario Research Foundation; Canada Research Chairs; National Heart, Lung, and Blood Institute; Heart and Stroke Foundation of Canada","keywords":"Biomaterial; Biocompatibility; Context (archaeology); Chemistry; In vivo; Citric acid; Implant; Biocompatible material; Biomedical engineering; Biochemistry; Surgery; Medicine; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001378116,0.0003246419,0.0001666688,0.0001488789,0.0000532343,0.0001908008,0.0001090636,0.0002784974,0.0007051522],"category_scores_gemma":[0.0001802171,0.0001233291,0.0001736021,0.00008934917,0.0001613792,0.0002252846,0.0001151363,0.0002717325,0.00009434513],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001014123,"about_ca_system_score_gemma":0.00008861528,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002036195,"about_ca_topic_score_gemma":0.0003287243,"domain_scores_codex":[0.9999071,0.00001384335,0.00001006,0.00002204684,0.0000232175,0.00002370453],"domain_scores_gemma":[0.9998395,0.00002984859,0.00007459356,0.00001194581,0.00001576164,0.00002825167],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008777592,0.00002292053,0.00004839036,0.00001868119,0.000001573736,0.00001743239,0.000006438328,0.00002425364,0.9993724,0.00000807729,0.00000335936,0.0003887019],"study_design_scores_gemma":[0.00001461484,0.000995882,0.002526429,0.000004116782,0.0000113894,0.00009448628,0.00001487244,0.0005174667,0.9954193,0.000007463777,0.0003911911,0.000002817503],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981899,0.0005616191,0.000885746,0.00001770837,0.00001135362,0.00001596825,0.00002313999,0.00001600243,0.0002787041],"genre_scores_gemma":[0.99642,0.0005399741,0.001734107,0.00004349052,0.000008760408,0.00002763224,0.00007833514,0.00001167219,0.001136035],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007051522,"threshold_uncertainty_score":0.002358973,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01569195333874258,"score_gpt":0.2579443375767216,"score_spread":0.242252384237979,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}