{"id":"W4389945058","doi":"10.1161/circ.148.suppl_1.14752","title":"Abstract 14752: FGF-23, Cardiovascular Events, and the Benefit of Canagliflozin in the CANVAS Trial","year":2023,"lang":"en","type":"article","venue":"Circulation","topic":"Fibroblast Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University of Toronto","funders":"","keywords":"Medicine; Mace; Canagliflozin; Hazard ratio; Internal medicine; Proportional hazards model; Clinical endpoint; Quartile; Fibroblast growth factor 23; Diabetes mellitus; Randomized controlled trial; Gastroenterology; Type 2 diabetes; Confidence interval; Endocrinology; Myocardial infarction; Percutaneous coronary intervention","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001080269,0.00007731911,0.00012834,0.00005734497,0.00005691097,0.00001431585,0.0001639032,0.00008386318,0.000004486014],"category_scores_gemma":[0.0001945472,0.00005086918,0.0001264497,0.0002279962,0.00008032525,0.00000417903,0.00005467057,0.0000917263,0.000005883992],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001489829,"about_ca_system_score_gemma":0.00005230883,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00103566,"about_ca_topic_score_gemma":0.0004920646,"domain_scores_codex":[0.9990525,0.0001295523,0.0001819296,0.000186362,0.0002881695,0.0001614648],"domain_scores_gemma":[0.9994562,0.00006309889,0.00004629468,0.000367988,0.0000438174,0.00002264923],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.01906708,0.0003259646,0.327717,0.0007608045,0.002438399,0.00005122957,0.005164234,0.05983022,0.5386859,0.006587029,0.003835029,0.03553712],"study_design_scores_gemma":[0.01117719,0.00004392193,0.9826337,0.00001931863,0.00003027338,0.0000046948,0.0001948229,0.0004513457,0.002944515,0.0005689952,0.001829732,0.0001015115],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982418,0.0006164476,0.00002475257,0.0002462229,0.00007023816,0.0005550731,0.00001176071,0.000004832883,0.0002289147],"genre_scores_gemma":[0.9995514,0.0001057899,0.000003688067,0.00002048606,0.0001242111,0.00004336489,0.0001181216,0.00001052498,0.00002237056],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6549167,"threshold_uncertainty_score":0.2074385,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0225265488576743,"score_gpt":0.2674480659482659,"score_spread":0.2449215170905916,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}