{"id":"W4389956676","doi":"10.1161/circ.148.suppl_1.15741","title":"Abstract 15741: Long-Term Efficacy and Safety of Once-Weekly Semaglutide for Weight Loss in Individuals With Obesity or Overweight but Without Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials","year":2023,"lang":"en","type":"review","venue":"Circulation","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"","keywords":"Semaglutide; Medicine; Overweight; Weight loss; Randomized controlled trial; Placebo; Internal medicine; Meta-analysis; Type 2 diabetes; Relative risk; Diabetes mellitus; Adverse effect; Obesity; Confidence interval; Body mass index; Liraglutide; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0131988,0.002565141,0.02017579,0.007759538,0.0005788258,0.003456193,0.001919223,0.002555396,0.005321319],"category_scores_gemma":[0.03090886,0.001395512,0.02269088,0.007811021,0.0009726065,0.002245095,0.001325503,0.001891226,0.0004607701],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003051208,"about_ca_system_score_gemma":0.004376126,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005313793,"about_ca_topic_score_gemma":0.01167713,"domain_scores_codex":[0.9895052,0.004498357,0.003566748,0.0008661975,0.001358656,0.0002048561],"domain_scores_gemma":[0.9818524,0.0111086,0.005011077,0.0003501402,0.001424865,0.0002529236],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.002004143,0.00002317145,0.001073738,0.7619903,0.2186349,0.00009474524,0.00006798099,0.0002252302,0.000269342,0.0001143497,0.0009509158,0.01455113],"study_design_scores_gemma":[0.002286113,0.0003717049,0.003319095,0.1493931,0.8401065,0.0001686048,0.00007584575,0.0002300944,0.0002551398,0.0002971659,0.003453026,0.00004362173],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002349173,0.9955779,0.000400096,0.0002099686,0.0001832299,0.0005435919,0.0004407779,0.0000292437,0.0002659922],"genre_scores_gemma":[0.08127519,0.911813,0.002306885,0.001256943,0.0002583614,0.001877553,0.0006876245,0.00003437122,0.0004901156],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.02017579,"threshold_uncertainty_score":0.0698027,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0902491528993612,"score_gpt":0.3629101776418813,"score_spread":0.2726610247425201,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}