{"id":"W4389976597","doi":"10.20944/preprints202312.1468.v1","title":"Construction and Immunogenicity of SARS-CoV-2 Virus-like Particle Expressed by Recombinant Baculovirus BacMam","year":2023,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health","keywords":"Virology; Immunogenicity; Neutralization; Virus-like particle; Virus; Recombinant DNA; Antibody; Biology; Adjuvant; Immune system; Immunology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004697712,0.0004241885,0.0002312759,0.0002912651,0.0001751201,0.0003573041,0.0003063506,0.0003956248,0.0005841135],"category_scores_gemma":[0.0003245803,0.0001541195,0.0003685782,0.0002999416,0.0002039366,0.0002284596,0.0002484276,0.0006267742,0.0003486098],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004241855,"about_ca_system_score_gemma":0.0001682438,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005266668,"about_ca_topic_score_gemma":0.0003459172,"domain_scores_codex":[0.999761,0.00006422286,0.00002910758,0.00003982785,0.00007192963,0.00003381494],"domain_scores_gemma":[0.9999073,0.00001985289,0.00002006602,0.000017071,0.00002113706,0.00001472262],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005945486,0.0000454374,0.0001678817,0.00002838434,0.000005478756,0.00003533637,0.00002263873,0.0001104744,0.998907,0.0001027563,0.00002143868,0.0004938022],"study_design_scores_gemma":[0.00002794901,0.0005460645,0.001987583,0.000006575819,0.00001902194,0.0001605521,0.00002322084,0.001210803,0.9936114,0.00005570811,0.002345228,0.00000585087],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933849,0.0005855794,0.004431998,0.00006083446,0.00004079005,0.0001383388,0.0004505006,0.00003656842,0.0008705205],"genre_scores_gemma":[0.9803877,0.0005904373,0.01223782,0.00007812485,0.00002565469,0.0001498044,0.003472496,0.00003986446,0.00301805],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005841135,"threshold_uncertainty_score":0.003077745,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1852496238809185,"score_gpt":0.4014778029551909,"score_spread":0.2162281790742723,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}