{"id":"W4389980929","doi":"10.1039/d3cc04782b","title":"Fluorescent molecular rotors detect <i>O</i><sup>6</sup>-methylguanine dynamics and repair in duplex DNA","year":2023,"lang":"en","type":"article","venue":"Chemical Communications","topic":"Molecular Sensors and Ion Detection","field":"Chemistry","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada; Canada Foundation for Innovation","keywords":"Fluorescence; Duplex (building); DNA; Chemistry; Dynamics (music); Biophysics; Molecular biology; Physics; Biology; Optics; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003449586,0.0005363252,0.0003011847,0.0001765403,0.0001997465,0.0004561267,0.0007135223,0.0009170129,0.002546855],"category_scores_gemma":[0.001084765,0.0002406018,0.0002253802,0.0001435186,0.0008391101,0.0006686864,0.000328765,0.0007988065,0.0007560635],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003142671,"about_ca_system_score_gemma":0.0002292436,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000197051,"about_ca_topic_score_gemma":0.0002792354,"domain_scores_codex":[0.9997185,0.00005129435,0.00001296159,0.0000945713,0.00007132581,0.00005140017],"domain_scores_gemma":[0.9993213,0.0001845237,0.0002485566,0.00006757439,0.0001002307,0.00007783373],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008699149,0.00001573081,0.0001143723,0.0000353705,0.000004498721,0.00001943202,0.00003234794,0.00005066083,0.9973967,0.0003844869,0.000100709,0.001758659],"study_design_scores_gemma":[0.000007981194,0.0001918125,0.0003625672,0.00000293999,0.000006005283,0.00007190705,0.0000205503,0.0004096771,0.9973904,0.00004079295,0.001489266,0.000006004561],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9285273,0.001884997,0.06150479,0.0003426268,0.0001744994,0.0001327833,0.0002500819,0.001131601,0.006051366],"genre_scores_gemma":[0.9594518,0.0006437268,0.03437097,0.0001748931,0.00002535308,0.00008317421,0.0003178908,0.0001548022,0.004777409],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002546855,"threshold_uncertainty_score":0.008520067,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01418368328668203,"score_gpt":0.2545140321086538,"score_spread":0.2403303488219718,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}