{"id":"W4389992286","doi":"10.3390/cells13010019","title":"Promising and Minimally Invasive Biomarkers: Targeting Melanoma","year":2023,"lang":"en","type":"article","venue":"Cells","topic":"Melanoma and MAPK Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Melanoma; Tumour heterogeneity; Biomarker; Medicine; Targeted therapy; Liquid biopsy; Immunotherapy; Cancer; Bioinformatics; Computational biology; Biology; Cancer research; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001628945,0.0001033832,0.00008989067,0.00004054325,0.00007217051,0.00002762118,0.00008562759,0.00009275746,0.0000159146],"category_scores_gemma":[0.00007360062,0.00009849543,0.00003752896,0.00008408813,0.000044762,0.000002595509,0.0001269969,0.000035704,0.00007556933],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003876712,"about_ca_system_score_gemma":0.00004597988,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005713609,"about_ca_topic_score_gemma":0.000005755021,"domain_scores_codex":[0.9992998,0.00003125951,0.0001199668,0.0002724595,0.00006112065,0.0002153606],"domain_scores_gemma":[0.9996865,0.00002151638,0.00004354911,0.0001460812,0.00002713257,0.00007520902],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001930653,0.000007312948,0.001224358,0.00003505858,0.00002674458,0.00002204156,0.00008689501,0.000001414958,0.9850348,0.00001218781,0.01227918,0.001250696],"study_design_scores_gemma":[0.0002726377,0.0001386897,0.001478895,0.00001569641,0.000008734575,0.000007194099,0.0002043977,0.0000347606,0.9716129,0.00005232037,0.02602936,0.0001443755],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953822,0.0004514046,0.0000312604,0.00007183393,0.0001732886,0.0001311291,0.00001175263,0.00002912251,0.003717998],"genre_scores_gemma":[0.9971025,0.0002006817,0.0009804884,0.0001060294,0.0001965335,0.0000111833,0.0001165598,0.00002033826,0.001265678],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01375018,"threshold_uncertainty_score":0.4016527,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01148199352098975,"score_gpt":0.2214415800887308,"score_spread":0.2099595865677411,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}