{"id":"W4390035530","doi":"10.3390/ijns10010001","title":"Droplet Digital PCR (ddPCR) Does Not Enhance the Sensitivity of Detection of Cytomegalovirus (CMV) DNA in Newborn Dried Blood Spots Evaluated in the Context of Newborn Congenital CMV (cCMV) Screening","year":2023,"lang":"en","type":"article","venue":"International Journal of Neonatal Screening","topic":"Cytomegalovirus and herpesvirus research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"University of Minnesota; Centers for Disease Control and Prevention; Minnesota Department of Health","keywords":"Digital polymerase chain reaction; Multiplex; Dried blood; Cytomegalovirus; Medicine; Context (archaeology); Real-time polymerase chain reaction; Primer (cosmetics); Newborn screening; Multiplex polymerase chain reaction; Virology; Dried blood spot; Polymerase chain reaction; Pediatrics; Biology; Bioinformatics; Genetics; Virus; Chemistry; Herpesviridae; Chromatography; Viral disease","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003324937,0.0002476941,0.0006818181,0.000961011,0.00006784325,0.00006957031,0.0005882793,0.0001426381,0.00006854119],"category_scores_gemma":[0.001638037,0.0001600601,0.0003623381,0.001039032,0.0004758958,0.0005764987,0.0002339534,0.0009003469,0.000006280305],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009286156,"about_ca_system_score_gemma":0.0002424394,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003038654,"about_ca_topic_score_gemma":0.003085441,"domain_scores_codex":[0.9953281,0.0003687678,0.001457084,0.0002731236,0.00219017,0.0003827819],"domain_scores_gemma":[0.9958532,0.001646206,0.0009512481,0.000275697,0.001163439,0.0001101376],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.006649258,0.0002801899,0.02470844,0.00004998048,0.0006923137,0.00109023,0.003590455,0.0005713865,0.4244663,0.00004976532,0.00002768022,0.537824],"study_design_scores_gemma":[0.01070584,0.001169897,0.3993048,0.001450301,0.0002261785,0.001548502,0.01587293,0.01864008,0.5463623,0.000182395,0.00416346,0.0003732669],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920258,0.0001955733,0.005431606,0.001238901,0.0001933936,0.0004156218,0.0003161806,0.00001303067,0.0001698748],"genre_scores_gemma":[0.9987617,0.0001121698,0.0006007992,0.0001149219,0.0002594465,0.000006818895,0.00003760566,0.00003159222,0.00007494268],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5374507,"threshold_uncertainty_score":0.6527061,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0333582278634196,"score_gpt":0.3234009830487995,"score_spread":0.2900427551853799,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}