{"id":"W4390035530","doi":"10.3390/ijns10010001","title":"Droplet Digital PCR (ddPCR) Does Not Enhance the Sensitivity of Detection of Cytomegalovirus (CMV) DNA in Newborn Dried Blood Spots Evaluated in the Context of Newborn Congenital CMV (cCMV) Screening","year":2023,"lang":"en","type":"article","venue":"International Journal of Neonatal Screening","topic":"Cytomegalovirus and herpesvirus research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"University of Minnesota; Centers for Disease Control and Prevention; Minnesota Department of Health","keywords":"Digital polymerase chain reaction; Multiplex; Dried blood; Cytomegalovirus; Medicine; Context (archaeology); Real-time polymerase chain reaction; Primer (cosmetics); Newborn screening; Multiplex polymerase chain reaction; Virology; Dried blood spot; Polymerase chain reaction; Pediatrics; Biology; Bioinformatics; Genetics; Virus; Chemistry; Herpesviridae; Chromatography; Viral disease","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0041186,0.0005236247,0.0007605481,0.0007565435,0.000249604,0.001203733,0.0005489662,0.0009590956,0.000937809],"category_scores_gemma":[0.008355573,0.0005432773,0.0003894167,0.0006359963,0.0008382941,0.0006555957,0.0004798481,0.000618487,0.000580778],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004724379,"about_ca_system_score_gemma":0.0002713305,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005526606,"about_ca_topic_score_gemma":0.0009346112,"domain_scores_codex":[0.9935313,0.001857697,0.0004956247,0.00159123,0.002321241,0.0002029325],"domain_scores_gemma":[0.9941255,0.00383281,0.0007477252,0.0003860609,0.0008131519,0.00009470987],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005681041,0.0001339328,0.03486674,0.0005675664,0.00008963494,0.0001850638,0.0004139552,0.0008030263,0.9080734,0.0003571126,0.0003004902,0.05364092],"study_design_scores_gemma":[0.00003009506,0.001512194,0.03780577,0.00007008645,0.0001487859,0.002784586,0.0002691371,0.0108595,0.9427515,0.0002799787,0.003446338,0.00004207468],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8855413,0.007510618,0.0991521,0.0004101458,0.0003939214,0.0003203007,0.0005924922,0.0006326073,0.005446486],"genre_scores_gemma":[0.8906056,0.001656283,0.1047072,0.0005810768,0.00005614253,0.0001539389,0.0004450809,0.00005619491,0.001738537],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0041186,"threshold_uncertainty_score":0.0217815,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0333582278634196,"score_gpt":0.3234009830487995,"score_spread":0.2900427551853799,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}