{"id":"W4390045983","doi":"10.1038/s41467-023-44163-5","title":"Hypothalamic CRH neurons represent physiological memory of positive and negative experience","year":2023,"lang":"en","type":"article","venue":"Nature Communications","topic":"Stress Responses and Cortisol","field":"Neuroscience","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; University of Calgary","funders":"Canadian Institutes of Health Research; Cumming School of Medicine, University of Calgary; Alberta Innovates; Government of Canada; Fondation Brain Canada; Brain and Behavior Research Foundation","keywords":"Neuroscience; Stimulus (psychology); Recall; Valence (chemistry); Psychology; Aversive Stimulus; Salient; Cognitive psychology; Computer science; Chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007445974,0.0001449465,0.000143691,0.0001185499,0.0000791847,0.0002714358,0.0001715061,0.0002283144,0.000640241],"category_scores_gemma":[0.0001704438,0.00008744419,0.00008111393,0.00004309325,0.0003702623,0.000217277,0.0001831754,0.0003784991,0.00008024778],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002023828,"about_ca_system_score_gemma":0.00008185724,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004339801,"about_ca_topic_score_gemma":0.0009272171,"domain_scores_codex":[0.999951,0.000003141566,0.000002117689,0.00001792986,0.00001185861,0.000013936],"domain_scores_gemma":[0.9999156,0.00001113405,0.00002220584,0.000009275559,0.00001144719,0.00003037564],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001259325,0.0000108748,0.001625145,0.00001416481,0.000004267959,0.00003257945,0.00002864963,0.00003170992,0.9957131,0.000152635,0.00002138543,0.002239492],"study_design_scores_gemma":[0.00003326564,0.0007137656,0.2707866,0.00002259059,0.00002220545,0.0004812513,0.000249707,0.001703132,0.7236827,0.001197646,0.001088205,0.00001886655],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971083,0.0002249923,0.001432306,0.00004260064,0.0000203178,0.000004566293,0.00006585845,0.00002211319,0.001078993],"genre_scores_gemma":[0.9981775,0.00008328599,0.000855624,0.00003574411,0.000007198119,0.000005128471,0.0000526978,0.000005600578,0.0007773657],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000640241,"threshold_uncertainty_score":0.002141833,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07249450274053709,"score_gpt":0.3582094386301433,"score_spread":0.2857149358896062,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}