{"id":"W4390054927","doi":"10.1002/epi4.12885","title":"Efficacy and Safety of adjunctive Perampanel in a prospective, real‐world, Phase IV study in Indian patients aged ≥12 years for Treatment of focal‐onset Epilepsy: Study 508","year":2023,"lang":"en","type":"article","venue":"Epilepsia Open","topic":"Epilepsy research and treatment","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Eisai Canada; Eisai","keywords":"Perampanel; Epilepsy; Medicine; Adjunctive treatment; Real world evidence; Pediatrics; Internal medicine; Psychiatry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008616658,0.0003218655,0.001281001,0.0008328998,0.00008385345,0.00002820079,0.0002328268,0.0000715736,0.00005374474],"category_scores_gemma":[0.0002912446,0.000264298,0.0001017678,0.001148623,0.000123027,0.0001503853,0.0002217152,0.0001531097,0.000009959033],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000501978,"about_ca_system_score_gemma":0.0002876557,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00478698,"about_ca_topic_score_gemma":0.01526461,"domain_scores_codex":[0.9970005,0.0004189359,0.0008478335,0.0007316496,0.0004664631,0.0005345959],"domain_scores_gemma":[0.9983512,0.0004817124,0.0002113127,0.0005842875,0.0001255416,0.0002459882],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.02412212,0.04034878,0.8954812,0.00005853276,0.0005041532,0.0003785347,0.02594449,0.000006908957,0.0000289295,0.00001033355,0.0001093804,0.01300661],"study_design_scores_gemma":[0.115255,0.0355332,0.8415193,0.0001654292,0.0001350273,0.000001365129,0.00702873,0.00003341791,0.00007904381,0.00005834644,0.00003276024,0.0001583123],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.97361,0.00003240931,6.40962e-7,0.00008819962,0.00004740503,0.02535765,0.0003871496,0.00002434161,0.0004521687],"genre_scores_gemma":[0.9961645,0.0001209541,0.0001362,0.00001042379,0.00002100875,0.002655247,0.0003531714,0.00004965046,0.0004888172],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09113292,"threshold_uncertainty_score":0.9999809,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05463963198867033,"score_gpt":0.3906628460389153,"score_spread":0.3360232140502449,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}