{"id":"W4390054927","doi":"10.1002/epi4.12885","title":"Efficacy and Safety of adjunctive Perampanel in a prospective, real‐world, Phase IV study in Indian patients aged ≥12 years for Treatment of focal‐onset Epilepsy: Study 508","year":2023,"lang":"en","type":"article","venue":"Epilepsia Open","topic":"Epilepsy research and treatment","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Eisai Canada; Eisai","keywords":"Perampanel; Epilepsy; Medicine; Adjunctive treatment; Real world evidence; Pediatrics; Internal medicine; Psychiatry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002058641,0.0007632072,0.001187253,0.0002565861,0.0002906451,0.0006849279,0.0006899534,0.0005848255,0.001542016],"category_scores_gemma":[0.001537054,0.0003933659,0.001038638,0.0006170427,0.0005642773,0.0005590234,0.0003271103,0.001368309,0.0004371158],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005510167,"about_ca_system_score_gemma":0.001211262,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009982736,"about_ca_topic_score_gemma":0.002884844,"domain_scores_codex":[0.9992046,0.0004502305,0.00007128465,0.00009836906,0.000085241,0.00009036395],"domain_scores_gemma":[0.9982358,0.0002599717,0.0007070036,0.0001576285,0.0002041485,0.0004354189],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.5539895,0.05167016,0.273793,0.001919286,0.005834661,0.000873431,0.001122796,0.001252162,0.03916566,0.0001370206,0.002444094,0.06779824],"study_design_scores_gemma":[0.234565,0.3438489,0.409585,0.0001169377,0.003122196,0.001439586,0.0004172858,0.0009710041,0.00282905,0.00008838289,0.002914564,0.0001021714],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980525,0.000538235,0.0001171443,0.00007136487,0.00001244097,0.0003332607,0.0004407697,0.00001812732,0.00041616],"genre_scores_gemma":[0.9968975,0.0006232349,0.00050742,0.0002824673,0.00005273176,0.0004041336,0.0009885806,0.00000614414,0.0002377588],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002058641,"threshold_uncertainty_score":0.01088727,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05463963198867033,"score_gpt":0.3906628460389153,"score_spread":0.3360232140502449,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}