{"id":"W4390065682","doi":"10.1016/s2213-2600(23)00374-0","title":"Adaptive servo-ventilation for sleep-disordered breathing in patients with heart failure with reduced ejection fraction (ADVENT-HF): a multicentre, multinational, parallel-group, open-label, phase 3 randomised controlled trial","year":2023,"lang":"en","type":"article","venue":"The Lancet Respiratory Medicine","topic":"Obstructive Sleep Apnea Research","field":"Medicine","cited_by":97,"is_retracted":false,"has_abstract":false,"ca_institutions":"Mount Sinai Hospital; McGill University Health Centre; Toronto General Hospital; Toronto Rehabilitation Institute; University Health Network","funders":"Canadian Institutes of Health Research; University Health Network","keywords":"Ejection fraction; Heart failure; Medicine; Epworth Sleepiness Scale; Randomized controlled trial; Cardiology; Clinical endpoint; Polysomnography; Internal medicine; Breathing; Physical therapy; Anesthesia; Apnea","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001685216,0.002053381,0.003593283,0.0003708208,0.000433213,0.001136555,0.001105195,0.001785256,0.006501168],"category_scores_gemma":[0.001612768,0.0005419184,0.003169159,0.0004067948,0.001393784,0.001149675,0.0005851715,0.002816402,0.0007298712],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005959033,"about_ca_system_score_gemma":0.0008513198,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001694227,"about_ca_topic_score_gemma":0.003614306,"domain_scores_codex":[0.9994472,0.0002613139,0.00004446326,0.0001108672,0.000040854,0.0000953961],"domain_scores_gemma":[0.9994251,0.000199724,0.0001212737,0.00005538404,0.00003605259,0.0001625349],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9891381,0.00175589,0.0003133303,0.0006828271,0.0009939468,0.00001898628,0.00003915272,0.0001737067,0.0009988495,0.00008544174,0.000368573,0.005431251],"study_design_scores_gemma":[0.9860675,0.01246406,0.0007309648,0.00002485984,0.0003000599,0.000008519264,0.00001388776,0.000139119,0.00006397624,0.00005438263,0.0001250286,0.000007732319],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9851577,0.006432749,0.001101043,0.0006849052,0.0007929757,0.003260172,0.001044573,0.0001393827,0.001386513],"genre_scores_gemma":[0.9805635,0.003883453,0.003049681,0.00138731,0.0005678991,0.005672149,0.001334105,0.00003464908,0.003507257],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006501168,"threshold_uncertainty_score":0.0217486,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06380344579498173,"score_gpt":0.3670933002058737,"score_spread":0.303289854410892,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}