{"id":"W4390125626","doi":"10.1101/2023.12.21.572837","title":"A Novel Pathway Implicated in Regulating Cognitive disfunction in a <i>Drosophila</i> Alzheimer’s Disease Model through Acer Inhibition and CG2233 Modulation","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Disease; Neuroscience; Dementia; Transgene; Medicine; Mechanism (biology); Neuroprotection; Bioinformatics; Biology; Internal medicine; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":{"n_in":0,"stratum":"aff_core","weight":5595.2375,"opus":{"tier":"OUT","genre":"empirical","about_ca":false,"confidence":"high","reason":"Drosophila model of Alzheimer's disease and ACE inhibition; a biomedical mechanism question."},"gpt":{"tier":"OUT","genre":"empirical","about_ca":false,"confidence":"high","reason":"The study investigates biological mechanisms in an Alzheimer's disease model rather than research practice."},"grok":{"tier":"OUT","genre":"empirical","about_ca":false,"confidence":"high","reason":"Drosophila Alzheimer disease model biology; object is disease pathways, not research practice."}}}