{"id":"W4390141524","doi":"10.1155/2023/6610007","title":"Renewable Human Cell Model for Type 1 Diabetes Research: EndoC-βH5/HUVEC Coculture Spheroids","year":2023,"lang":"en","type":"article","venue":"Journal of Diabetes Research","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Spheroid; Islet; In vitro; Cell culture; Insulin; Beta cell; Transplantation; Biology; Diabetes mellitus; Cell; Chemistry; Internal medicine; Endocrinology; Medicine; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004647887,0.0004906321,0.0005410843,0.0004042887,0.0003056682,0.0006286591,0.0004029824,0.0004792926,0.001809734],"category_scores_gemma":[0.0001759892,0.000183524,0.0004591404,0.0005738277,0.0001960076,0.0002653454,0.0003365789,0.0009413052,0.00114936],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003601103,"about_ca_system_score_gemma":0.0003323317,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001694598,"about_ca_topic_score_gemma":0.00292058,"domain_scores_codex":[0.9993713,0.0000830636,0.00007849422,0.0001573318,0.0002229064,0.00008691982],"domain_scores_gemma":[0.9997358,0.00005289148,0.00004285129,0.00006652552,0.00005237678,0.00004952222],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002367339,0.0002097504,0.001456624,0.0002479172,0.00003362956,0.0004412559,0.0001893441,0.0006447386,0.9895181,0.000720706,0.001530439,0.004770754],"study_design_scores_gemma":[0.00003103262,0.0005840568,0.00752095,0.00005362554,0.000074925,0.001020673,0.00009882698,0.003177487,0.9689334,0.0001359149,0.01833868,0.00003031057],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9032027,0.008210205,0.05594367,0.0005464074,0.00080113,0.0006756412,0.0109859,0.001082084,0.01855216],"genre_scores_gemma":[0.9199921,0.005279662,0.05210228,0.0004483076,0.00009850889,0.001008441,0.01266186,0.0001502584,0.008258537],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001809734,"threshold_uncertainty_score":0.006054223,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2827726444639668,"score_gpt":0.4570099119146535,"score_spread":0.1742372674506867,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}