{"id":"W4390141524","doi":"10.1155/2023/6610007","title":"Renewable Human Cell Model for Type 1 Diabetes Research: EndoC-βH5/HUVEC Coculture Spheroids","year":2023,"lang":"en","type":"article","venue":"Journal of Diabetes Research","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Spheroid; Islet; In vitro; Cell culture; Insulin; Beta cell; Transplantation; Biology; Diabetes mellitus; Cell; Chemistry; Internal medicine; Endocrinology; Medicine; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008026106,0.0002534233,0.0008016981,0.001309091,0.0006464453,0.0001810969,0.0005245667,0.0002820058,0.0003953139],"category_scores_gemma":[0.004640223,0.0001933392,0.0003411145,0.002421154,0.0003939052,0.00028376,0.0002137557,0.001537739,0.0002485526],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003058463,"about_ca_system_score_gemma":0.0007966147,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001590515,"about_ca_topic_score_gemma":0.00000780055,"domain_scores_codex":[0.9942123,0.0004765031,0.0007903202,0.0004059498,0.00238339,0.001731487],"domain_scores_gemma":[0.9919842,0.002167657,0.0001990627,0.0005715713,0.004333219,0.0007443131],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001689289,0.0003471375,0.02267566,0.0006297526,0.0002039526,0.00002151528,0.0004306737,0.0007998061,0.5231167,0.0001147078,0.4507926,0.0006985539],"study_design_scores_gemma":[0.01369699,0.01387549,0.009405109,0.002079103,0.000383188,0.00001019665,0.004344786,0.1126122,0.6824211,0.02312561,0.1371735,0.0008727027],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9834413,0.002229815,0.00001838444,0.00203997,0.0002997665,0.000786849,0.00003179213,0.00007238783,0.01107974],"genre_scores_gemma":[0.9314459,0.0004254097,0.001395522,0.0002257375,0.001114963,0.00009180939,0.00006404971,0.00009493818,0.06514166],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.313619,"threshold_uncertainty_score":0.7884144,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2827726444639668,"score_gpt":0.4570099119146535,"score_spread":0.1742372674506867,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}