{"id":"W4390192909","doi":"10.1002/alz.076540","title":"Safety profile of semaglutide in people aged 55 years and over: pooled data from the PIONEER, SUSTAIN and STEP phase 3 clinical programmes","year":2023,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"LMC Diabetes & Endocrinology (Canada); Toronto Public Health","funders":"","keywords":"Semaglutide; Overweight; Medicine; Placebo; Obesity; Body mass index; Clinical trial; Weight loss; Internal medicine; Type 2 diabetes; Gerontology; Physical therapy; Diabetes mellitus; Endocrinology; Liraglutide; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01730234,0.00119245,0.003376954,0.001652983,0.0003330821,0.001309777,0.0006015549,0.00100166,0.003216426],"category_scores_gemma":[0.02097991,0.0005043818,0.01027756,0.002398505,0.0003809215,0.0008787421,0.001160158,0.000955259,0.0004887676],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005646214,"about_ca_system_score_gemma":0.001143208,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00164764,"about_ca_topic_score_gemma":0.002373995,"domain_scores_codex":[0.9863467,0.006830818,0.002563435,0.001668027,0.002238017,0.0003530163],"domain_scores_gemma":[0.9856004,0.004709096,0.005622742,0.001444071,0.002277605,0.0003462144],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.3431194,0.0009134607,0.1734918,0.02787056,0.3535034,0.0002618413,0.0005357886,0.002325799,0.003734177,0.000350889,0.01281469,0.08107822],"study_design_scores_gemma":[0.06220215,0.02872716,0.5338216,0.003445894,0.3504587,0.0006152695,0.0002889615,0.001720197,0.001836706,0.001040392,0.01560078,0.0002421735],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7779065,0.1210481,0.009534054,0.0005580752,0.0004186133,0.006108554,0.07692385,0.0004033718,0.007098955],"genre_scores_gemma":[0.9553882,0.00860412,0.002321319,0.0007180782,0.0002375688,0.003988117,0.02748545,0.00006103984,0.001196005],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01730234,"threshold_uncertainty_score":0.09150463,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04423079381061202,"score_gpt":0.3458721182519409,"score_spread":0.3016413244413289,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}