{"id":"W4390193316","doi":"10.1002/alz.076116","title":"Early detection of mild cognitive impairment due to Alzheimer’s disease using combinations of an online cognitive assessment and blood biomarkers","year":2023,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Cognitive impairment; Receiver operating characteristic; Montreal Cognitive Assessment; Internal medicine; Area under the curve; Oncology; Disease; Amyloid beta; Cognition; Biomarker; Alzheimer's disease; Pathology; Gastroenterology; Audiology; Psychiatry; Biology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001715695,0.001254219,0.0007216969,0.001542873,0.0002031597,0.0009646992,0.0003269512,0.0005177517,0.0008713038],"category_scores_gemma":[0.003152952,0.0002145835,0.0005877051,0.0006447625,0.0001608179,0.0004662953,0.0003952256,0.0004063606,0.0002742221],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002561136,"about_ca_system_score_gemma":0.0002721333,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001235578,"about_ca_topic_score_gemma":0.001937879,"domain_scores_codex":[0.9992957,0.0003237458,0.00006054101,0.0001530606,0.0001184637,0.00004848748],"domain_scores_gemma":[0.9986264,0.0004611556,0.0003514299,0.0001156226,0.0003154894,0.0001299521],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001684307,0.0005073599,0.9182885,0.0001230046,0.0006252834,0.0001661149,0.00007890513,0.001980472,0.006886611,0.00008538386,0.0006752597,0.06889868],"study_design_scores_gemma":[0.00008890139,0.002820869,0.938303,0.00007199584,0.000785468,0.001443479,0.000158882,0.04083149,0.01295784,0.001044397,0.001428104,0.0000655454],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9899129,0.001556935,0.006215489,0.0001339664,0.00004191082,0.00005903534,0.0007026417,0.000190302,0.001186826],"genre_scores_gemma":[0.9946651,0.0002275832,0.004332125,0.00005509961,0.00003973171,0.00003894744,0.0002873441,0.000004529546,0.0003494542],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001715695,"threshold_uncertainty_score":0.009073555,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06051326184333903,"score_gpt":0.3709041749594757,"score_spread":0.3103909131161366,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}