{"id":"W4390193961","doi":"10.4274/tjps.galenos.2023.72430","title":"Evaluation of a Synthetic PEI-based Polymeric Vector for ING4 Gene Delivery to MCF-7 Breast Cancer Cells","year":2023,"lang":"en","type":"article","venue":"Turkish Journal of Pharmaceutical Sciences","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Türkiye Bilimsel ve Teknolojik Araştırma Kurumu; University of Alberta","keywords":"Viability assay; MCF-7; Gene delivery; Western blot; Transfection; Molecular biology; Genetic enhancement; Cancer cell; Cell; Cell culture; Cancer; Breast cancer; Cell growth; Biology; Cancer research; Chemistry; Gene; Biochemistry; Genetics; Human breast","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002747175,0.0002753345,0.0001586075,0.0002231175,0.00009415819,0.0002013926,0.0001620148,0.0002753111,0.000458689],"category_scores_gemma":[0.0002390442,0.00009231279,0.0001460927,0.0001592575,0.0001337907,0.0002075777,0.0001046758,0.00019411,0.0001385636],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003172383,"about_ca_system_score_gemma":0.0001641704,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004599096,"about_ca_topic_score_gemma":0.0004664126,"domain_scores_codex":[0.9998767,0.00003090884,0.00001267515,0.00002569647,0.00004022463,0.00001382512],"domain_scores_gemma":[0.999909,0.00002311265,0.00002746374,0.000004816987,0.00002456592,0.00001110185],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005889317,0.00002237329,0.0001023927,0.00008210387,0.000004740526,0.00003476347,0.00001705544,0.0001476431,0.9973645,0.00005423661,0.00002244068,0.002089024],"study_design_scores_gemma":[0.000006549375,0.0006124644,0.0005572225,0.000004900915,0.00001714805,0.00009347596,0.00001285177,0.0008672678,0.9961309,0.00001027112,0.001683368,0.000003607982],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9882421,0.001997948,0.008205336,0.00008721794,0.00003575558,0.0001019538,0.0001605368,0.00007885732,0.001090244],"genre_scores_gemma":[0.9750988,0.001867323,0.01897642,0.00004742779,0.000009549467,0.0001091219,0.0005797783,0.00002551647,0.003285976],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004599096,"threshold_uncertainty_score":0.002301812,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07816741779847083,"score_gpt":0.3960840741485462,"score_spread":0.3179166563500754,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}