{"id":"W4390193961","doi":"10.4274/tjps.galenos.2023.72430","title":"Evaluation of a Synthetic PEI-based Polymeric Vector for ING4 Gene Delivery to MCF-7 Breast Cancer Cells","year":2023,"lang":"en","type":"article","venue":"Turkish Journal of Pharmaceutical Sciences","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Türkiye Bilimsel ve Teknolojik Araştırma Kurumu; University of Alberta","keywords":"Viability assay; MCF-7; Gene delivery; Western blot; Transfection; Molecular biology; Genetic enhancement; Cancer cell; Cell; Cell culture; Cancer; Breast cancer; Cell growth; Biology; Cancer research; Chemistry; Gene; Biochemistry; Genetics; Human breast","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001822503,0.0001066383,0.0001656368,0.0001483614,0.00008178474,0.00002811751,0.000353929,0.00005288202,0.0001106031],"category_scores_gemma":[0.0001266247,0.00008322417,0.0001431024,0.0003967386,0.0001624333,0.0000123851,0.00005083051,0.00006519488,0.000007024632],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003280014,"about_ca_system_score_gemma":0.0005116387,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001831118,"about_ca_topic_score_gemma":0.00000719522,"domain_scores_codex":[0.9984612,0.0001156546,0.0003171491,0.0002069724,0.0006344655,0.0002645837],"domain_scores_gemma":[0.9988548,0.00005825816,0.0001718516,0.00008625284,0.0006714987,0.0001573705],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001895309,0.00005159766,0.0003619923,0.00001513559,0.00004570105,0.000001581697,0.00003588933,0.006341717,0.9633112,0.00000231253,0.001315359,0.02832798],"study_design_scores_gemma":[0.000588309,0.0005455745,0.002308352,0.00006247457,0.000166314,0.00002111869,0.00009557146,0.01196978,0.9832103,0.00003418118,0.0008786244,0.0001194397],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964061,0.001183871,0.0005029456,0.001100464,0.0005044336,0.0001805342,0.00007609315,0.000004082716,0.00004146001],"genre_scores_gemma":[0.9986866,0.0002534516,0.0003140092,0.0004207043,0.00027873,0.00001582774,0.000003126408,0.000007481023,0.00002013926],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02820854,"threshold_uncertainty_score":0.3393783,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07816741779847083,"score_gpt":0.3960840741485462,"score_spread":0.3179166563500754,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}