{"id":"W4390194686","doi":"10.1002/advs.202301358","title":"Mesoporous Silica Nanoparticles Mediate SiRNA Delivery for Long‐Term Multi‐Gene Silencing in Intact Plants","year":2023,"lang":"en","type":"article","venue":"Advanced Science","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics and Developmental Biology, Chinese Academy of Sciences; Chinese Academy of Sciences; Institute of Genetics; National Natural Science Foundation of China","keywords":"Gene silencing; RNA interference; Gene knockdown; Small interfering RNA; Cell biology; Biology; Phytoene desaturase; Chemistry; Gene; RNA; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001070816,0.0002664817,0.0001730983,0.0001166908,0.0001335064,0.0001756101,0.0001762989,0.0003109646,0.0004220782],"category_scores_gemma":[0.00007024014,0.0001529214,0.0002214121,0.00005445181,0.0001587084,0.0002273896,0.0001964455,0.0002803499,0.0002718144],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003060501,"about_ca_system_score_gemma":0.0001736113,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008144148,"about_ca_topic_score_gemma":0.001474102,"domain_scores_codex":[0.9999365,0.000005543111,0.000005364637,0.0000205334,0.00001995374,0.00001214329],"domain_scores_gemma":[0.9999424,0.00001096419,0.00001882532,0.000005296271,0.00001093955,0.00001146052],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000007142588,0.000002684536,0.000009462239,0.00000972355,0.000001169539,0.000007684424,0.000003404892,0.00002707346,0.9995829,0.00002642222,0.00001013712,0.0003121497],"study_design_scores_gemma":[0.000003741464,0.00004470766,0.0002722152,0.000001227723,0.000004407071,0.00002509832,0.000003981313,0.0008881066,0.9977919,0.00001287401,0.0009492337,0.000002585763],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9662574,0.001922634,0.02798634,0.0001109427,0.00007461489,0.00009433258,0.0002089213,0.0003383584,0.003006468],"genre_scores_gemma":[0.986878,0.0006228266,0.008847771,0.00004432555,0.00001112727,0.00005196514,0.0001417513,0.00003878064,0.003363424],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008144148,"threshold_uncertainty_score":0.002220571,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02273536717021922,"score_gpt":0.3048159540801777,"score_spread":0.2820805869099585,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}