{"id":"W4390195474","doi":"10.1002/alz.077450","title":"A systematic evaluation of cortical GABA levels in transgenic mouse models of amyloid","year":2023,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"GABA and Rice Research","field":"Agricultural and Biological Sciences","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"PSEN1; Presenilin; Hippocampal formation; Amyloid precursor protein; Genetically modified mouse; Neuroscience; GABAergic; Amyloid (mycology); Glutamatergic; Cortex (anatomy); Transgene; Biology; Alzheimer's disease; Medicine; Internal medicine; Disease; Pathology; Gene; Biochemistry; Glutamate receptor; Inhibitory postsynaptic potential; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007911598,0.001022529,0.004654341,0.01539083,0.0006150866,0.001830981,0.001308411,0.001156059,0.002607177],"category_scores_gemma":[0.01451397,0.0005893593,0.004019211,0.01062584,0.0008275959,0.001722478,0.001359264,0.0005981834,0.0004555974],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00177709,"about_ca_system_score_gemma":0.004760499,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002181592,"about_ca_topic_score_gemma":0.00687588,"domain_scores_codex":[0.9938877,0.001270436,0.003089789,0.0006596099,0.000945116,0.0001473425],"domain_scores_gemma":[0.9820472,0.007798457,0.005525719,0.0008217558,0.003466574,0.0003403914],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"observational","study_design_scores_codex":[0.001484272,0.00009052251,0.009242709,0.837893,0.01085387,0.0009304227,0.0004688748,0.0001327812,0.009462119,0.0007842483,0.003171164,0.1254859],"study_design_scores_gemma":[0.0009347741,0.002612062,0.05175356,0.6500499,0.129715,0.004310355,0.001155506,0.0002082132,0.00912761,0.001572152,0.148388,0.0001728303],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.01543842,0.9768003,0.001268889,0.0005052933,0.0002430772,0.001168752,0.003198223,0.00005138243,0.001325598],"genre_scores_gemma":[0.1023015,0.8792517,0.006532809,0.001774472,0.0002311635,0.003821369,0.004917411,0.00006648512,0.001103069],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.01539083,"threshold_uncertainty_score":0.04184103,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1541220642199182,"score_gpt":0.3293763379416553,"score_spread":0.1752542737217371,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}