{"id":"W4390198527","doi":"10.1002/alz.077554","title":"Validated, unified theory of Alzheimer Disease illuminates two essential research questions","year":2023,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Alcoholism and Thiamine Deficiency","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Manitoba Beekeepers' Association","funders":"","keywords":"Thiamine; Alzheimer's disease; Disease; Medicine; Thiamine deficiency; Internal medicine; Neuroscience; Physiology; Endocrinology; Psychology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02355986,0.001548401,0.003053661,0.005931666,0.002272747,0.007043483,0.003999634,0.00558506,0.006071471],"category_scores_gemma":[0.02007129,0.0005785007,0.001514478,0.002463183,0.02613477,0.01518899,0.005979709,0.009661051,0.001781836],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.005330215,"about_ca_system_score_gemma":0.007998108,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003110248,"about_ca_topic_score_gemma":0.001740702,"domain_scores_codex":[0.9896801,0.005501422,0.000892821,0.00147404,0.001972677,0.0004787859],"domain_scores_gemma":[0.9732162,0.01727938,0.001366246,0.002950218,0.004101691,0.001086305],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.00008017512,0.00009127202,0.001195928,0.00129255,0.00008815269,0.0002707542,0.001226586,0.0004529184,0.0002023858,0.936305,0.01393103,0.04486309],"study_design_scores_gemma":[0.00002440438,0.00006774148,0.0009201733,0.001297941,0.00004401998,0.0003625095,0.0006683039,0.0007094637,0.0001143056,0.9597526,0.03600477,0.0000337804],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.01183334,0.3817646,0.1019131,0.4197477,0.0162211,0.0003078397,0.001031968,0.0002534245,0.06692696],"genre_scores_gemma":[0.4799071,0.2493896,0.1140436,0.1130508,0.02937476,0.001611409,0.001591595,0.0001641373,0.01086702],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.02355986,"threshold_uncertainty_score":0.1245979,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0865768442055328,"score_gpt":0.3839002575098297,"score_spread":0.2973234133042969,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}