{"id":"W4390199130","doi":"10.1002/alz.073279","title":"The role of the biofilm of Porphyromonas gingivalis in driving amyloid beta secretion and aggregation","year":2023,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Oral microbiology and periodontitis research","field":"Dentistry","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Porphyromonas gingivalis; Biofilm; Thioflavin; Microbiology; Extracellular matrix; Bacteria; Secretion; Fluorescence microscope; Chemistry; Neuroinflammation; Amyloid beta; Atomic force microscopy; Extracellular; Biology; Inflammation; Cell biology; Fluorescence; Immunology; Medicine; Materials science; Pathology; Alzheimer's disease; Biochemistry; Nanotechnology; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001661422,0.000350304,0.0001874817,0.0001381882,0.0004357882,0.0006186674,0.0001750884,0.0004975456,0.0007900312],"category_scores_gemma":[0.0002333567,0.0001351339,0.0001944112,0.00009999562,0.0002047299,0.000319161,0.0004642511,0.0005956262,0.0002899645],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003449943,"about_ca_system_score_gemma":0.0003328568,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001846789,"about_ca_topic_score_gemma":0.001341405,"domain_scores_codex":[0.9998502,0.00002070357,0.000008512521,0.0000231776,0.00005251988,0.00004487673],"domain_scores_gemma":[0.9998813,0.00002762486,0.00003069521,0.000009209293,0.00002210809,0.00002902353],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003544567,0.00002418211,0.0005102623,0.00006586594,0.000002429235,0.0001017693,0.00004469925,0.0000820987,0.9977221,0.0001457511,0.00008557562,0.00117992],"study_design_scores_gemma":[0.00003438194,0.0007686259,0.0279717,0.00008119357,0.00002433014,0.0007419878,0.0008871602,0.006767008,0.9551153,0.001037672,0.006540184,0.0000302942],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925508,0.003199576,0.001727533,0.0005325676,0.00005970655,0.00003453119,0.000247815,0.00003943668,0.001607819],"genre_scores_gemma":[0.996325,0.00102486,0.001744541,0.00006023165,0.0000144067,0.00002327662,0.00008471502,0.000005447258,0.0007174644],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001846789,"threshold_uncertainty_score":0.003672063,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01772054859525203,"score_gpt":0.2739238721181385,"score_spread":0.2562033235228865,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}