{"id":"W4390199564","doi":"10.1002/alz.080181","title":"Plasma biomarkers as stand‐alone tests in the diagnosis of Alzheimer’s disease","year":2023,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Bipolar Disorder and Treatment","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; Montreal Neurological Institute and Hospital; McGill University","funders":"","keywords":"Dementia; Medicine; Internal medicine; Disease; Biomarker; Oncology; Predictive value; Diagnostic biomarker; Alzheimer's disease; Cognitive impairment; Positive predicative value; Diagnostic accuracy; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.009813556,0.001710593,0.001422371,0.003255849,0.0004734726,0.003282654,0.0009428724,0.001610823,0.00137385],"category_scores_gemma":[0.01882034,0.000629948,0.0006572871,0.001961686,0.0006450394,0.001420123,0.0007634964,0.001301195,0.001065668],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005341778,"about_ca_system_score_gemma":0.0007860673,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001030694,"about_ca_topic_score_gemma":0.001660429,"domain_scores_codex":[0.9944132,0.003266538,0.0004118287,0.0006881778,0.001032682,0.0001876526],"domain_scores_gemma":[0.9833577,0.009854127,0.002425102,0.0008590172,0.002833591,0.0006704064],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003321873,0.0001756961,0.8186617,0.0008201545,0.0009697377,0.0009636026,0.0002664039,0.00174633,0.007288145,0.0005883244,0.007426584,0.1577714],"study_design_scores_gemma":[0.000414267,0.004205483,0.8601338,0.001777417,0.00240261,0.009696231,0.0009571589,0.04185162,0.03145748,0.01213356,0.0346467,0.0003236716],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7678136,0.1758133,0.02273775,0.006029845,0.002103469,0.0002345253,0.004695128,0.001017771,0.01955464],"genre_scores_gemma":[0.9793558,0.005280932,0.01225159,0.0007847493,0.0006433741,0.00009124307,0.0006568132,0.00003675534,0.0008987277],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009813556,"threshold_uncertainty_score":0.05189967,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04055159906502644,"score_gpt":0.3088276858193557,"score_spread":0.2682760867543293,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}