{"id":"W4390200894","doi":"10.1002/alz.073336","title":"Changing the trajectory of Alzheimer’s disease: What is a meaningful delay in disease progression?","year":2023,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Health Science Centre","funders":"","keywords":"Medicine; Clinical trial; Disease; Placebo; Dementia; Internal medicine; Oncology; Pathology; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02032596,0.0006548167,0.001235676,0.0009355409,0.0006277247,0.00313435,0.0008387212,0.00123975,0.002430744],"category_scores_gemma":[0.06479607,0.0002272547,0.001553419,0.0009913873,0.001795352,0.003680526,0.0008347891,0.002567179,0.000336771],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002356548,"about_ca_system_score_gemma":0.00198294,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001508436,"about_ca_topic_score_gemma":0.00149463,"domain_scores_codex":[0.9892385,0.007107869,0.001145884,0.0007600586,0.001498802,0.0002488611],"domain_scores_gemma":[0.9611572,0.02486471,0.007756151,0.001718559,0.003156134,0.001347162],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.01901668,0.001314195,0.2032429,0.01418304,0.003563758,0.0004254652,0.002203277,0.01016291,0.006799522,0.04557091,0.01259625,0.6809211],"study_design_scores_gemma":[0.002196195,0.01646344,0.6024573,0.01283552,0.004172024,0.00195517,0.005373922,0.02054398,0.01550515,0.2482846,0.06980395,0.000408861],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"commentary","genre_scores_codex":[0.5318367,0.297232,0.0715914,0.0708044,0.002546053,0.0007264144,0.003648385,0.0003071922,0.0213073],"genre_scores_gemma":[0.9757674,0.01106994,0.009525675,0.002032324,0.0006027524,0.0002277337,0.0003938163,0.00003328751,0.000347147],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.02032596,"threshold_uncertainty_score":0.1074952,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04154826581819439,"score_gpt":0.3396276284780019,"score_spread":0.2980793626598075,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}