{"id":"W4390225284","doi":"10.1136/thorax-2023-220292","title":"Elevated ferritin, mediated by IL-18 is associated with systemic inflammation and mortality in acute respiratory distress syndrome (ARDS)","year":2023,"lang":"en","type":"review","venue":"Thorax","topic":"Iron Metabolism and Disorders","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Efficacy and Mechanism Evaluation Programme; Queen's University; Academy of Medical Sciences; Queen's University Belfast; Department for the Economy; Biotechnology and Biological Sciences Research Council; Department of Health and Social Care; Wellcome Trust; National Institute for Health and Care Research; Medical Research Council; Public Health Agency; National Heart, Lung, and Blood Institute; National Institute for Social Care and Health Research","keywords":"Medicine; ARDS; Ferritin; Internal medicine; Prospective cohort study; Biomarker; Sepsis; Gastroenterology; Lung","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003103985,0.0005279686,0.0008368882,0.0005906282,0.0001962554,0.0005939467,0.0003824922,0.0004554268,0.001484677],"category_scores_gemma":[0.005305112,0.0002297846,0.00222918,0.0008024979,0.0003192158,0.000247306,0.0004679062,0.0009164761,0.0001207007],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002973764,"about_ca_system_score_gemma":0.0004647836,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001466905,"about_ca_topic_score_gemma":0.001825708,"domain_scores_codex":[0.9989027,0.0005009694,0.0001276987,0.0002169576,0.0001698055,0.00008193499],"domain_scores_gemma":[0.9949137,0.002006706,0.002222429,0.0003090264,0.0003619744,0.0001861432],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"systematic_review","study_design_scores_codex":[0.00651285,0.0001004046,0.9652074,0.001297007,0.008975809,0.0001573508,0.00006881952,0.0006289861,0.001292748,0.0001013105,0.0006311432,0.01502621],"study_design_scores_gemma":[0.0005096978,0.001012075,0.9836669,0.0003933718,0.009514438,0.0007434211,0.00006395661,0.001619394,0.0007661856,0.0004527681,0.001239569,0.00001822563],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.9532657,0.04194377,0.001396974,0.0008915787,0.00008209109,0.00003650024,0.001685422,0.00003738563,0.0006605852],"genre_scores_gemma":[0.995352,0.003288176,0.0004469355,0.00008831163,0.00007385542,0.00002744403,0.0005816146,0.000004800973,0.0001368752],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.003103985,"threshold_uncertainty_score":0.01641566,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04817985577689689,"score_gpt":0.3414640748505711,"score_spread":0.2932842190736742,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}