{"id":"W4390236694","doi":"10.3390/pharmaceutics16010032","title":"Overview of Tissue Engineering and Drug Delivery Applications of Reactive Electrospinning and Crosslinking Techniques of Polymeric Nanofibers with Highlights on Their Biocompatibility Testing and Regulatory Aspects","year":2023,"lang":"en","type":"review","venue":"Pharmaceutics","topic":"Electrospun Nanofibers in Biomedical Applications","field":"Materials Science","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Nuclear Laboratories","funders":"Qatar National Research Fund; Qatar University; Fonds National de la Recherche Luxembourg; Qatar Foundation","keywords":"Electrospinning; Nanofiber; Drug delivery; Materials science; Nanotechnology; Tissue engineering; Biocompatibility; Polymer; Biomedical engineering; Composite material; Engineering","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003586552,0.001050815,0.0008972718,0.003037148,0.000254914,0.0006175475,0.0005239425,0.000736392,0.002519803],"category_scores_gemma":[0.0002501741,0.0004541157,0.0005644888,0.002176301,0.0002978593,0.001059947,0.0003658764,0.001144964,0.001458326],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004419833,"about_ca_system_score_gemma":0.0007257879,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007539321,"about_ca_topic_score_gemma":0.001178244,"domain_scores_codex":[0.9998178,0.00001911427,0.00002645279,0.00004195888,0.00007799928,0.00001679541],"domain_scores_gemma":[0.9998342,0.0000748282,0.00002525273,0.000007812328,0.00004624691,0.00001160429],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006720644,0.0001920004,0.0001924532,0.032218,0.0001108108,0.0003484891,0.0001160796,0.0007857563,0.03429042,0.007763394,0.01704041,0.906875],"study_design_scores_gemma":[0.00001012071,0.0002608524,0.0009476963,0.002642932,0.0001139464,0.001816773,0.00004010239,0.0002350401,0.00934644,0.001311957,0.9832414,0.00003283125],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005790832,0.9923425,0.001103054,0.0001274099,0.0001786504,0.00002736507,0.00005311266,0.00002649912,0.005562331],"genre_scores_gemma":[0.002439745,0.9932784,0.001573702,0.0001683031,0.000134038,0.00003214119,0.00009138124,0.000005117063,0.002277154],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003037148,"threshold_uncertainty_score":0.008429646,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0614237215354427,"score_gpt":0.3565347127855822,"score_spread":0.2951109912501395,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}