{"id":"W4390236694","doi":"10.3390/pharmaceutics16010032","title":"Overview of Tissue Engineering and Drug Delivery Applications of Reactive Electrospinning and Crosslinking Techniques of Polymeric Nanofibers with Highlights on Their Biocompatibility Testing and Regulatory Aspects","year":2023,"lang":"en","type":"review","venue":"Pharmaceutics","topic":"Electrospun Nanofibers in Biomedical Applications","field":"Materials Science","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Nuclear Laboratories","funders":"Qatar National Research Fund; Qatar University; Fonds National de la Recherche Luxembourg; Qatar Foundation","keywords":"Electrospinning; Nanofiber; Drug delivery; Materials science; Nanotechnology; Tissue engineering; Biocompatibility; Polymer; Biomedical engineering; Composite material; Engineering","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006310943,0.0003535358,0.001134878,0.0002618551,0.0001077435,0.00002117463,0.0002410041,0.000139991,0.000001861359],"category_scores_gemma":[0.0000304215,0.0002801861,0.00004989337,0.0009987971,0.0006257537,0.00007475791,0.0001845956,0.0002367631,4.053154e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008778682,"about_ca_system_score_gemma":0.0001748981,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006869207,"about_ca_topic_score_gemma":0.000003189881,"domain_scores_codex":[0.998065,0.00008542827,0.0007406455,0.0005325619,0.0002820437,0.0002943294],"domain_scores_gemma":[0.9972345,0.001194535,0.0009223281,0.000387044,0.0001492953,0.0001123596],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000164163,0.0001032405,0.00005982152,0.03245768,0.0001419764,0.000001396936,0.0002621108,8.836624e-7,0.6101678,0.001513995,0.000005530042,0.3552691],"study_design_scores_gemma":[0.0001734608,0.0001721736,0.00009059152,0.01023689,0.0005346273,0.00002919874,0.00001426207,0.0000785418,0.9706274,0.0004454646,0.01722569,0.0003716854],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.025859,0.9711505,0.0006742591,0.00002344978,0.0000273014,0.001912726,0.0001462417,0.0001594414,0.00004707184],"genre_scores_gemma":[0.01487382,0.9547365,0.02994685,0.00001321464,0.00005005675,0.0002769835,0.00001816775,0.00007714814,0.000007250727],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.3604596,"threshold_uncertainty_score":0.999965,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0614237215354427,"score_gpt":0.3565347127855822,"score_spread":0.2951109912501395,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}