{"id":"W4390241019","doi":"10.4103/jdds.jdds_8_23","title":"A 60-week Real-world Experience with Guselkumab in Patients with Moderate-to-Severe Plaque Psoriasis Including Patients with Malignancy: A Retrospective Study from Ontario, Canada","year":2023,"lang":"en","type":"article","venue":"Journal of Dermatology & Dermatologic Surgery","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Plaque psoriasis; Medicine; Malignancy; Psoriasis; Dermatology; Retrospective cohort study; Surgery; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007790255,0.0002970216,0.0005766527,0.00122836,0.002013099,0.001299106,0.0007934444,0.0005530177,0.002363683],"category_scores_gemma":[0.002618824,0.0004763109,0.000478695,0.003198679,0.0009104902,0.0006274935,0.0006113016,0.0006710645,0.000395122],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.005352894,"about_ca_system_score_gemma":0.006566057,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.5535431,"about_ca_topic_score_gemma":0.6306869,"domain_scores_codex":[0.9987914,0.0001152151,0.0001453833,0.0001977643,0.0004848996,0.0002653406],"domain_scores_gemma":[0.9955616,0.0004722413,0.001951952,0.0001659548,0.001115351,0.0007328579],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.000111334,0.00008051845,0.9930935,0.00007062303,0.00004447746,0.00186092,0.001236696,0.00001441855,0.0002174724,0.00003125688,0.0006342769,0.002604493],"study_design_scores_gemma":[0.00002419562,0.0002101982,0.9880747,0.00009048061,0.00006458185,0.005468382,0.003234388,0.00009802712,0.00007656796,0.00001746169,0.002615266,0.00002575409],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946794,0.002298908,0.00008874966,0.000438453,0.00001729103,0.0000653527,0.0006972777,0.00000462214,0.001709817],"genre_scores_gemma":[0.9961636,0.002064684,0.0001074295,0.0004750731,0.00006157281,0.00001891175,0.000535269,0.00000815741,0.0005653697],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4464569,"threshold_uncertainty_score":0.8981724,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01933725643659487,"score_gpt":0.2218555486523578,"score_spread":0.202518292215763,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}