{"id":"W4390261963","doi":"10.1016/j.jns.2023.121629","title":"Ubrogepant for the acute treatment of migraine when administred during the prodrome: Results from a phase 3, randomized, double-blind, placebo-controlled, crossover study","year":2023,"lang":"en","type":"article","venue":"Journal of the Neurological Sciences","topic":"Migraine and Headache Studies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"ABB (Canada)","funders":"","keywords":"Prodrome; Placebo; Crossover study; Migraine; Double blind; Randomized controlled trial; Medicine; Psychiatry; Psychology; Pediatrics; Internal medicine; Psychosis; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002203494,0.001449853,0.003851169,0.0007487333,0.0007126086,0.001198405,0.001387124,0.002294753,0.004630707],"category_scores_gemma":[0.002320679,0.0008901284,0.001884124,0.0007649824,0.002343273,0.001649965,0.0003824716,0.003330054,0.0008083331],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006141578,"about_ca_system_score_gemma":0.001861984,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001241955,"about_ca_topic_score_gemma":0.00216871,"domain_scores_codex":[0.9990674,0.0004612618,0.0000776808,0.0001345875,0.00009489662,0.0001642929],"domain_scores_gemma":[0.9981572,0.0007632748,0.0003320945,0.0001346782,0.0001091778,0.0005035491],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9683189,0.01257149,0.0003577691,0.0007106963,0.0006379894,0.00006477703,0.00008379909,0.0001373848,0.004668785,0.00007280563,0.0002879172,0.01208752],"study_design_scores_gemma":[0.8918792,0.1047916,0.001787211,0.00002736526,0.0003935975,0.00003417584,0.00002697263,0.0001424994,0.0005941507,0.00006050297,0.0002460287,0.00001678153],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9898224,0.0052777,0.0008426344,0.0002399454,0.0003196474,0.001875475,0.0005596097,0.000119843,0.0009428427],"genre_scores_gemma":[0.9873056,0.005446141,0.002017792,0.0007180969,0.0006177684,0.00166299,0.0007785528,0.0000554309,0.001397579],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004630707,"threshold_uncertainty_score":0.01549131,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1004502022577146,"score_gpt":0.3842975699660627,"score_spread":0.2838473677083481,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}