{"id":"W4390263338","doi":"10.1097/tp.0000000000004877","title":"Distinct Molecular Processes Mediate Donor-derived Cell-free DNA Release From Kidney Transplants in Different Disease States","year":2023,"lang":"en","type":"article","venue":"Transplantation","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"The Metabolomics Innovation Centre; University of Alberta","funders":"Natera","keywords":"DNA; Disease; Cell-free fetal DNA; Cell; Kidney; Medicine; Biology; Cell biology; Cancer research; Computational biology; Genetics; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001205654,0.0002401732,0.0003922249,0.000845863,0.0001612612,0.0007637666,0.0002311871,0.00025616,0.001504991],"category_scores_gemma":[0.001662324,0.000144816,0.000304361,0.0004670577,0.000312306,0.000376302,0.0003967972,0.000413907,0.0002869887],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003321109,"about_ca_system_score_gemma":0.0002680179,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003168822,"about_ca_topic_score_gemma":0.0004832985,"domain_scores_codex":[0.9991623,0.000226191,0.00007303121,0.0001951332,0.0002274546,0.0001158392],"domain_scores_gemma":[0.9989547,0.0002343185,0.0005231223,0.00008045464,0.00009310622,0.0001142928],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.007654626,0.0002305967,0.7684246,0.0002637577,0.0003613997,0.0002486767,0.0002694901,0.0004347556,0.1865743,0.0003159278,0.0002984532,0.03492336],"study_design_scores_gemma":[0.00005306429,0.0007396903,0.9686911,0.0000266712,0.0001413319,0.0007013775,0.0001588694,0.001207804,0.02733177,0.0002601634,0.0006767736,0.00001137677],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965709,0.001563286,0.0009211224,0.00004517936,0.000009015703,0.00001964296,0.0003447226,0.00001756946,0.0005086249],"genre_scores_gemma":[0.9985072,0.000224372,0.0005409468,0.00003207451,0.00001065172,0.00001765168,0.0005205817,0.000006828745,0.0001397918],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001504991,"threshold_uncertainty_score":0.006376207,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01398242268221476,"score_gpt":0.2581622906220438,"score_spread":0.244179867939829,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}