{"id":"W4390267056","doi":"10.3390/cells13010057","title":"Reduction in Nuclear Size by DHRS7 in Prostate Cancer Cells and by Estradiol Propionate in DHRS7-Depleted Cells","year":2023,"lang":"en","type":"article","venue":"Cells","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"European Research Council; Medical Research Council; Canadian Institutes of Health Research; Sigrid Juséliuksen Säätiö; Academy of Finland; Darwin Trust of Edinburgh; Wellcome Trust","keywords":"LNCaP; Prostate cancer; Prostate; Cancer research; Cancer; Grading (engineering); Cancer cell; Biology; Estrogen; Internal medicine; Endocrinology; Oncology; Medicine; Chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002699663,0.0002312832,0.0003784221,0.0002899971,0.00004442483,0.00003597588,0.00009297139,0.0001393437,0.0001209915],"category_scores_gemma":[0.0000152145,0.0001996902,0.0000388479,0.0009483192,0.0001425955,0.0001347873,0.00005592679,0.0004439926,0.00009856727],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004105958,"about_ca_system_score_gemma":0.0001642229,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001701384,"about_ca_topic_score_gemma":0.0001154173,"domain_scores_codex":[0.9980511,0.00009847362,0.0003714699,0.000554194,0.0002955311,0.0006292302],"domain_scores_gemma":[0.9994379,0.00007334648,0.00006635845,0.000210163,0.00003866411,0.0001735576],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000593918,0.000278225,0.007450134,0.0003305387,0.00002376916,0.0003221538,0.001960531,0.00006415495,0.9464456,0.00000228944,0.03655784,0.005970792],"study_design_scores_gemma":[0.0123952,0.0005793931,0.01407698,0.0007966978,0.00003638619,0.000008757859,0.001750892,0.001602776,0.9311998,0.0001500299,0.03685484,0.0005481858],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927933,0.002525903,1.438127e-7,0.002144184,0.0002618109,0.001588791,0.0001368693,0.00007393178,0.000475062],"genre_scores_gemma":[0.9661093,0.02405968,0.00004591977,0.0001105494,0.00005783138,0.0002099456,0.00009523638,0.00007039058,0.009241173],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02668403,"threshold_uncertainty_score":0.8143131,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01250126032434544,"score_gpt":0.2775931987321805,"score_spread":0.265091938407835,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}