{"id":"W4390298149","doi":"10.20944/preprints202312.2125.v1","title":"Homing and Engraftment of Hematopoietic Stem Cells Following Transplantation:
A Pre-clinical Perspective","year":2023,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa; Canadian Blood Services","funders":"","keywords":"Homing (biology); Stem cell; Haematopoiesis; Biology; Transplantation; Bone marrow; Paracrine signalling; Hematopoietic stem cell; Immunology; Niche; Stem cell factor; Hematopoietic stem cell transplantation; Progenitor cell; Cell biology; Cancer research; Medicine; Internal medicine; Genetics; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001879093,0.0004188859,0.0005094651,0.0004758593,0.0003066182,0.002157117,0.0006712433,0.001034798,0.01242329],"category_scores_gemma":[0.001281324,0.0001530937,0.0002360703,0.0004426497,0.001206928,0.000949682,0.000945343,0.001643005,0.003884945],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006807811,"about_ca_system_score_gemma":0.0005365223,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005708979,"about_ca_topic_score_gemma":0.0006970652,"domain_scores_codex":[0.9996152,0.00009317827,0.00003134238,0.00005780827,0.0001535654,0.00004882786],"domain_scores_gemma":[0.999402,0.0001577455,0.0000770646,0.0001051397,0.0001450952,0.0001129146],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009130234,0.0003518282,0.006835563,0.001903509,0.00005135509,0.001242202,0.0003344853,0.0009404881,0.2015776,0.03625751,0.03044455,0.7191479],"study_design_scores_gemma":[0.00009065024,0.002408433,0.02559643,0.0009380832,0.00008023442,0.004876454,0.0007490087,0.001776853,0.2485302,0.02661256,0.6882747,0.0000663682],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.1995155,0.4362933,0.1010554,0.05782892,0.01130704,0.0004075123,0.003024823,0.002562374,0.1880052],"genre_scores_gemma":[0.5844772,0.2379027,0.065218,0.01068882,0.003059026,0.0002718848,0.002942326,0.0008126739,0.09462735],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.01242329,"threshold_uncertainty_score":0.04156011,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1535757955746955,"score_gpt":0.3996351991782556,"score_spread":0.2460594036035601,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}