{"id":"W4390430133","doi":"10.1007/s00011-023-01834-9","title":"Granulocyte macrophage colony stimulating factor exerts dominant effects over macrophage colony stimulating factor during macrophage differentiation in vitro to induce an inflammatory phenotype","year":2023,"lang":"en","type":"article","venue":"Inflammation Research","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Granulocyte macrophage colony-stimulating factor; Macrophage colony-stimulating factor; Proinflammatory cytokine; Macrophage; Cytokine; Colony-stimulating factor; Immunology; Haematopoiesis; Tumor necrosis factor alpha; Granulocyte macrophage colony-stimulating factor receptor; Inflammation; Biology; Phenotype; In vitro; Macrophage polarization; Hematopoietic growth factor; Cell biology; Stem cell; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.001916256,0.000603301,0.0007941762,0.001645602,0.00106586,0.0002467243,0.0007941992,0.0008168797,0.0009457658],"category_scores_gemma":[0.001665413,0.000625737,0.0001518289,0.001770013,0.0002717216,0.0007171595,0.0008309673,0.001876447,0.00187279],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001244746,"about_ca_system_score_gemma":0.0002426761,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004629844,"about_ca_topic_score_gemma":0.0002381378,"domain_scores_codex":[0.9928865,0.002119089,0.001274917,0.001152635,0.0006627194,0.001904093],"domain_scores_gemma":[0.9962171,0.00174819,0.0003735038,0.0009818034,0.0004890566,0.0001903679],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001662297,0.0000921764,0.01826505,0.0005334672,0.00008610176,0.0002476208,0.00476752,0.002626286,0.9583049,0.0000299898,0.00008979237,0.01329476],"study_design_scores_gemma":[0.002911553,0.0001950729,0.4011964,0.0001972766,0.00001106117,0.000005609315,0.0001292724,0.001958182,0.5926714,0.0000445237,0.0002718629,0.0004077648],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940777,0.0003351089,0.0001428032,0.00009859978,0.001481393,0.003261236,0.0001139338,0.0003377272,0.0001514402],"genre_scores_gemma":[0.9960043,0.00004485995,0.0001502981,0.00003303548,0.0002314394,0.0005924053,0.0003801588,0.0001510686,0.002412436],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3829314,"threshold_uncertainty_score":0.9999675,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03110971264502231,"score_gpt":0.3374953110955549,"score_spread":0.3063855984505325,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}