{"id":"W4390500174","doi":"10.1093/intimm/dxad056","title":"T-cell help in the germinal center: homing in on the role of IL-21","year":2024,"lang":"en","type":"article","venue":"International Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Wellcome Trust","keywords":"Germinal center; Homing (biology); Center (category theory); Chemistry; Cell biology; B cell; Immunology; Biology; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005086503,0.0002003731,0.0002506984,0.0003993357,0.00006796329,0.00002669829,0.001023421,0.0002786611,0.0007722481],"category_scores_gemma":[0.00007555598,0.0001255115,0.000130085,0.0002375039,0.0004193533,0.00008179791,0.0001808625,0.0009361655,0.0008480752],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008770786,"about_ca_system_score_gemma":0.00006732185,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004047015,"about_ca_topic_score_gemma":0.0001046676,"domain_scores_codex":[0.998278,0.0004557475,0.0004947282,0.0003275745,0.00006729174,0.0003766253],"domain_scores_gemma":[0.9985975,0.0009016076,0.0001064328,0.0003427458,0.00004665348,0.000005065478],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002554694,0.0004750175,0.002827879,0.000007471845,0.0001602187,0.00006148352,0.001756664,0.000008007039,0.9482791,0.03759864,0.0009743759,0.007595601],"study_design_scores_gemma":[0.00215157,0.0005493055,0.008048332,0.000232952,0.00002692752,0.0006849956,0.006004555,0.0001145112,0.5363401,0.006984456,0.4385434,0.0003189388],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9635203,0.01116696,0.000008198258,0.004167267,0.002306239,0.0002219742,0.00004562598,0.00003200701,0.01853135],"genre_scores_gemma":[0.9969606,0.000437793,0.000007851713,0.0003743299,0.00005097463,0.00006524744,0.00006750188,0.0000163298,0.002019328],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.437569,"threshold_uncertainty_score":0.9999299,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00915390670566078,"score_gpt":0.2335547035105184,"score_spread":0.2244007968048576,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}